Diabetic foot ulcers (DFUs) are very important diabetes-related lesions that can lead to
serious physical consequences like amputations of limbs and equally severe social …

Human epithelia are constantly exposed to microorganisms present in the environment or
residing as part of commensal flora. Despite this exposure, infections involving the skin and …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

The Centers for Disease Control and Prevention estimate for human infectious diseases
caused by bacteria with a biofilm phenotype is 65 percent and the National Institutes of …

The number of people in the world with diabetes has nearly quadrupled in the past 40 years.
Current data show that 25% of these diabetics will develop a foot ulcer in their lifetime and …

Increasing evidence within the literature has identified the presence of biofilms in chronic
wounds and proposed that they contribute to delayed wound healing. This research aimed …

Bacterial biofilms residing in chronic wounds are thought to have numerous survival
strategies, making them extremely difficult to eradicate and resulting in long-term infections …

We used next generation DNA sequencing to profile the microbiome of infected Diabetic
Foot Ulcers (DFUs). The microbiota was correlated to clinical parameters and treatment …

Diabetic foot ulcers (DFU) represent a growing public health problem. The emergence of
multidrug-resistant (MDR) bacteria is a complication due to the difficulties in distinguishing …

Objectives Clinicians have increasingly adopted the widespread use of topical agents to
manage chronic wound infections, despite limited data on their effectiveness in vivo. This …