Importance Cardiovascular disease and cancer are the 2 leading causes of death in the US,
and vitamin and mineral supplementation has been proposed to help prevent these …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

Background Vitamin D and related compounds have been used to prevent osteoporotic
fractures in older people. This is the third update of a Cochrane review first published in …

Context Vitamin D deficiency is highly prevalent across the world. The existing evidence
suggests vitamin D may have beneficial effects on serum lipid profiles and thus …

Vitamin D deficiency is typically caused by inadequate cutaneous synthesis secondary to
decreased exposure to sunlight. Serum levels of 25-hydroxyvitamin D l< 20 ng/ml are …

Importance Low levels of vitamin D are associated with elevated blood pressure (BP) and
future cardiovascular events. Whether vitamin D supplementation reduces BP and which …

Importance Low serum vitamin D levels have been associated with adverse clinical
outcomes; identifying and treating deficiency may improve outcomes. Objective To review …

Type 2 diabetes mellitus is a significant global health care problem, and pharmacotherapies
to treat the disease continue to emerge. However, the increasing burden of type 2 diabetes …

Context: Observational studies report consistent associations between low vitamin D
concentration and increased glycemia and risk of type 2 diabetes, but results of randomized …

Context: Public health authorities around the world recommend widely variable
supplementation strategies for adults, whereas several professional organizations, including …