Advances in surface plasmon resonance biosensor analysis

RL Rich, DG Myszka - Current opinion in biotechnology, 2000 - Elsevier
The number and diversity of surface plasmon resonance (SPR) biosensor applications
continue to increase. Evolutions in instrument and sensor chip technology, experimental …

Surface plasmon resonance: applications in understanding receptor-ligand interaction

P Pattnaik - Applied biochemistry and biotechnology, 2005 - Springer
During last decade there has been significant progress in the development of analytical
techniques for evaluation of receptor-ligand iteraction. Surface plasmon resonance (SPR) …

Exploring avidity: understanding the potential gains in functional affinity and target residence time of bivalent and heterobivalent ligands

G Vauquelin, SJ Charlton - British journal of pharmacology, 2013 - Wiley Online Library
Bivalent ligands are increasingly important therapeutic agents. Although the naturally
occurring antibodies are predominant, it is becoming more common to combine different …

[HTML][HTML] Real-time and label-free bio-sensing of molecular interactions by surface plasmon resonance: a laboratory medicine perspective

E Helmerhorst, DJ Chandler, M Nussio… - The Clinical …, 2012 - ncbi.nlm.nih.gov
Radioactive, chromogenic, fluorescent and other labels have long provided the basis of
detection systems for biomolecular interactions including immunoassays and receptor …

Extending the range of rate constants available from BIACORE: interpreting mass transport-influenced binding data

DG Myszka, X He, M Dembo, TA Morton, B Goldstein - Biophysical journal, 1998 - cell.com
Surface-based binding assays are often influenced by the transport of analyte to the sensor
surface. Using simulated data sets, we test a simple two-compartment model to see if its …

Mass transport and surface reactions in microfluidic systems

T Gervais, KF Jensen - Chemical engineering science, 2006 - Elsevier
We provide analysis of different regimes of diffusion and laminar flow convection combined
with bimolecular surface reactions relevant to biochemical assays performed in microfluidic …

Adsorption-induced conformational changes in fibronectin due to interactions with well-defined surface chemistries

KE Michael, VN Vernekar, BG Keselowsky… - Langmuir, 2003 - ACS Publications
Protein adsorption onto synthetic materials influences cell adhesion and signaling events
that direct cell function in numerous biomedical applications. Adsorption of fibronectin (FN) …

A universal biosensing platform based on optical micro-ring resonators

A Ramachandran, S Wang, J Clarke, SJ Ja… - Biosensors and …, 2008 - Elsevier
The use of optical micro-ring resonators as a platform for quantitative and qualitative
biosensing applications was explored. Vertically coupled, high refractive index micro-ring …

BIAcore for macromolecular interaction

M Fivash, EM Towler, RJ Fisher - Current opinion in biotechnology, 1998 - Elsevier
Examination of the literature for period of this review revealed nearly two hundred citations
that employed surface plasmon resonance (SPR) spectroscopy using BIAcore technology to …

[HTML][HTML] Data evaluation for surface-sensitive label-free methods to obtain real-time kinetic and structural information of thin films: A practical review with related …

A Saftics, S Kurunczi, B Peter, I Szekacs… - Advances in Colloid and …, 2021 - Elsevier
Interfacial layers are important in a wide range of applications in biomedicine, biosensing,
analytical chemistry and the maritime industries. Given the growing number of applications …