Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy
P Singh, KB Marcu, MB Goldring… - Annals of the New York …, 2019 - Wiley Online Library
Articular chondrocytes are quiescent, fully differentiated cells responsible for the
homeostasis of adult articular cartilage by maintaining cellular survival functions and the fine …
homeostasis of adult articular cartilage by maintaining cellular survival functions and the fine …
Exosomes and stem cells in degenerative disease diagnosis and therapy
YH Chang, KC Wu, HJ Harn, SZ Lin… - Cell …, 2018 - journals.sagepub.com
Stroke can cause death and disability, resulting in a huge burden on society. Parkinson's
disease (PD) is a chronic neurodegenerative disorder characterized by motor dysfunction …
disease (PD) is a chronic neurodegenerative disorder characterized by motor dysfunction …
[HTML][HTML] MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway
Y Ding, L Wang, Q Zhao, Z Wu… - … journal of molecular …, 2019 - spandidos-publications.com
Osteoarthritis (OA) is a serious disease of the articular cartilage, and inflammation has been
implicated in its pathogenesis. Previously, microRNAs (miRNAs) have been proposed as …
implicated in its pathogenesis. Previously, microRNAs (miRNAs) have been proposed as …
Role of MicroRNA, LncRNA, and exosomes in the progression of osteoarthritis: a review of recent literature
F Xie, Y Liu, X Chen, Q Li, J Zhong, B Dai… - Orthopaedic …, 2020 - Wiley Online Library
Osteoarthritis (OA) is a common clinical degenerative disease characterized by the
destruction of articular cartilage, which has an increasing impact on people's lives and social …
destruction of articular cartilage, which has an increasing impact on people's lives and social …
Signature of circulating microRNAs in osteoarthritis
Background Osteoarthritis is the most common form of arthritis and a major socioeconomic
burden. Our study is the first to explore the association between serum microRNA levels and …
burden. Our study is the first to explore the association between serum microRNA levels and …
The microRNA-29 family in cartilage homeostasis and osteoarthritis
LTT Le, TE Swingler, N Crowe, TL Vincent… - Journal of molecular …, 2016 - Springer
MicroRNAs have been shown to function in cartilage development and homeostasis, as well
as in progression of osteoarthritis. The objective of the current study was to identify …
as in progression of osteoarthritis. The objective of the current study was to identify …
Chondrocyte hypertrophy in skeletal development, growth, and disease
MMG Sun, F Beier - Birth Defects Research Part C: Embryo …, 2014 - Wiley Online Library
Most of our bones form through the process of endochondral ossification, which is tightly
regulated by the activity of the cartilage growth plate. Chondrocyte maturation through the …
regulated by the activity of the cartilage growth plate. Chondrocyte maturation through the …
Baicalin protects human OA chondrocytes against IL-1β-induced apoptosis and ECM degradation by activating autophagy via MiR-766-3p/AIFM1 Axis
Z Li, J Cheng, J Liu - Drug Design, Development and Therapy, 2020 - Taylor & Francis
Background Osteoarthritis (OA) is one of the most prevalent and degenerative diseases with
complicated pathology including articular cartilage degradation, subchondral sclerosis and …
complicated pathology including articular cartilage degradation, subchondral sclerosis and …
[HTML][HTML] Analysis of genetics and DNA methylation in osteoarthritis: what have we learnt about the disease?
LN Reynard - Seminars in Cell & Developmental Biology, 2017 - Elsevier
Osteoarthritis (OA) is a chronic musculoskeletal disease characterised by the destruction of
articular cartilage, synovial inflammation and bone remodelling. Disease aetiology is …
articular cartilage, synovial inflammation and bone remodelling. Disease aetiology is …
Emerging roles for long noncoding RNAs in skeletal biology and disease
Normal skeletal development requires tight coordination of transcriptional networks,
signaling pathways, and biomechanical cues, and many of these pathways are dysregulated …
signaling pathways, and biomechanical cues, and many of these pathways are dysregulated …