Recent advances in highthoughput DNA sequencing have made genomescale analyses
of genomes of extinct organisms possible. With these new opportunities come new …

Individual age estimation is a key factor in forensic science analysis that can provide very
useful information applicable to criminal, legal, and anthropological investigations. Forensic …

Dried plant herbarium specimens are potentially a valuable source of DNA. Efforts to obtain
genetic information from this source are often hindered by an inability to obtain amplifiable …

Abstract Background and Objectives As next-generation sequencing (NGS) becomes a
major sequencing platform in clinical diagnostic laboratories, it is critical to identify artifacts …

Ancient DNA (aDNA) research has long depended on the power of PCR to amplify trace
amounts of surviving genetic material from preserved specimens. While PCR permits …

Background Rodents are recognized as hosts for at least 60 zoonotic diseases and may
represent a serious threat for human health. In the context of global environmental changes …

The invention of next-generation-sequencing has revolutionized almost all fields of genetics,
but few have profited from it as much as the field of ancient DNA research. From its …

Archival tissues represent a rich resource for clinical genomic studies, particularly when
coupled with comprehensive medical records. Use of these in next generation sequencing …

Although ancient DNA from sediments (sedaDNA) has been used to investigate past
ecosystems, the approach has never been directly compared with the traditional methods of …

Epigenetic information is available from contemporary organisms, but is difficult to track back
in evolutionary time. Here, we show that genome-wide epigenetic information can be …