Autophagy is a well-known cell-survival strategy orchestrated by a conserved set of proteins.
It equips the cells with mechanisms to attain homeostasis during unfavorable conditions …

Colorectal cancer (CRC) is one of the most common human malignancies worldwide. Along
with apoptosis and inflammation, autophagy is one of three important mechanisms in CRC …

The Covid-19 pandemic driven by the SARS-CoV-2 virus continues to exert extensive
humanitarian and economic stress across the world. Although antivirals active against mild …

Autophagy is known as a conserved self-eating mechanism that contributes to cells to
degrade different intracellular components (ie, macromolecular complexes, aggregated …

Anticancer drug development is complex and multi-factorial, demanding robust drug
evaluative architecture in experimental and preclinical studies. To increase the number of …

Basal autophagy plays a crucial role in maintaining intracellular homeostasis and prevents
the cell from escaping the cell cycle regulation mechanisms and being cancerous …

COVID-19 pandemic situation has affected millions of people with tens of thousands of
deaths worldwide. Despite all efforts for finding drugs or vaccines, the key role for the …

Fucoidan, a natural polysaccharide with a variety of classical bioactivities mainly sourced
from brown algae, has been extensively studied owing to its favorable pharmacological …

Background Concurrent viral infections insist on dysregulated epigenetics of tumor
suppressor genes (TSGs), cell cycle regulators, apoptosis, and autophagy-associated genes …

Autophagy is a self-degradative process important for balancing cellular homeostasis at
critical times in development and/or in response to nutrient stress. This is particularly …