Wnt and PI3K/Akt/mTOR survival pathways as therapeutic targets in glioblastoma

A Barzegar Behrooz, Z Talaie, F Jusheghani… - International journal of …, 2022 - mdpi.com
Glioblastoma (GBM) is a devastating type of brain tumor, and current therapeutic treatments,
including surgery, chemotherapy, and radiation, are palliative at best. The design of effective …

Molecular mechanisms and cellular contribution from lung fibrosis to lung cancer development

AV Samarelli, V Masciale, B Aramini, GP Coló… - International journal of …, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease (ILD) of unknown aetiology, with a median survival of 2–4 years from the time of …

1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway

B Yu, XQ Jin, WY Yu, YY Dong, HZ Ying… - International …, 2021 - Elsevier
Inulae Flos was widely distributed throughout Europe, Africa, and Asia, and was commonly
used as a folk medicine in clinic for treating various respiratory diseases, including cough …

Alveolar epithelial type 2 cell dysfunction in idiopathic pulmonary fibrosis

W Zhu, C Tan, J Zhang - Lung, 2022 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible pulmonary interstitial
disease that seriously affects the patient's quality of life and lifespan. The pathogenesis of …

The regenerative power of stem cells: treating bleomycin-induced lung fibrosis

A Vats, P Chaturvedi - Stem Cells and Cloning: Advances and …, 2023 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with no known
cure, characterized by the formation of scar tissue in the lungs, leading to respiratory failure …

[PDF][PDF] Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis

V Ptasinski - 2023 - portal.research.lu.se
The lung is a vital organ in the body enabling us to breathe. During chronic lung diseases,
the function of the lung is impacted by damage to the tissue structure. Idiopathic pulmonary …