Human wound and its burden: updated 2020 compendium of estimates

CK Sen - Advances in wound care, 2021 - liebertpub.com
Significance: Chronic wounds impact the quality of life (QoL) of nearly 2.5% of the total
population in the United States and the management of wounds has a significant economic …

The insights of microbes' roles in wound healing: A comprehensive review

T Maheswary, AA Nurul, MB Fauzi - Pharmaceutics, 2021 - mdpi.com
A diverse range of normal flora populates the human skin and numbers are relatively
different between individuals and parts of the skin. Humans and normal flora have formed a …

pH/glucose dual responsive metformin release hydrogel dressings with adhesion and self-healing via dual-dynamic bonding for athletic diabetic foot wound healing

Y Liang, M Li, Y Yang, L Qiao, H Xu, B Guo - ACS nano, 2022 - ACS Publications
In view of the lack of a specific drug-sustained release system that is responsive to chronic
wounds of the type II diabetic foot, and the demands for frequent movement at the foot …

Ångstrom-scale silver particle–embedded carbomer gel promotes wound healing by inhibiting bacterial colonization and inflammation

CY Chen, H Yin, X Chen, TH Chen, HM Liu, SS Rao… - Science …, 2020 - science.org
Poor wound healing after diabetes or extensive burn remains a challenging problem.
Recently, we presented a physical approach to fabricate ultrasmall silver particles from …

Preparation of NIR-responsive, ROS-generating and antibacterial black phosphorus quantum dots for promoting the MRSA-infected wound healing in diabetic rats

S Huang, S Xu, Y Hu, X Zhao, L Chang, Z Chen, X Mei - Acta biomaterialia, 2022 - Elsevier
Abstract Multidrug-resistant (MDR) bacteria-induced infection is becoming a huge challenge
for clinical treatment, especially for non-healing diabetic wound infections, which increase …

A physicochemical double-cross-linked gelatin hydrogel with enhanced antibacterial and anti-inflammatory capabilities for improving wound healing

Y Lu, M Zhao, Y Peng, S He, X Zhu, C Hu, G Xia… - Journal of …, 2022 - Springer
Background Skin tissue is vital in protecting the body from injuries and bacterial infections.
Wound infection caused by bacterial colonization is one of the main factors hindering wound …

Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice

X Ding, Q Tang, Z Xu, Y Xu, H Zhang, D Zheng… - Burns & …, 2022 - academic.oup.com
Acute and chronic wound infection has become a major worldwide healthcare burden
leading to significantly high morbidity and mortality. The underlying mechanism of infections …

A hybrid hydrogel constructed using drug loaded mesoporous silica and multiple response copolymer as an intelligent dressing for wound healing of diabetic foot …

W Zhang, Z Yang, M Zhang, J He, S Li… - Journal of Materials …, 2023 - pubs.rsc.org
Traditional wound dressings have poor mechanical properties and a single function, which
cannot achieve rapid healing of diabetic wounds in a unique physiological …

Exosomal lncRNA KLF3-AS1 derived from bone marrow mesenchymal stem cells stimulates angiogenesis to promote diabetic cutaneous wound healing

ZF Han, JH Cao, ZY Liu, Z Yang, RX Qi… - Diabetes Research and …, 2022 - Elsevier
Aims We focused on BMSC-derived exosomal lncRNA KLF3-AS1 and its significance in
diabetic cutaneous wound healing. Methods Potential interaction between KLF3-AS1 and …

[HTML][HTML] Wound microenvironment-responsive glucose consumption and hydrogen peroxide generation synergistic with azithromycin for diabetic wounds healing

M Shi, Z Du, Y Qi, W Li, H Hu, X Lin, S Wang, Z Tang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Chronic wounds are one of the common complications of diabetes. Due to the
physiological conditions of diabetic patients, these wounds are more susceptible to bacterial …