Oral contraceptives and cycle control: a critical review of the literature

MJ Rosenberg, SC Long - Advances in contraception, 1992 - Springer
Control of spotting and breakthrough bleeding and absence of withdrawal bleeding,
collectively termed cycle control, is the single most important determinant of whether a new …

Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label …

J Endrikat, S Parke, D Trummer, W Schmidt, I Duijkers… - Contraception, 2008 - Elsevier
BACKGROUND: Attempts to improve the tolerability of combined oral contraceptives (COCs)
have included the substitution of ethinylestradiol (EE) with 17β-estradiol (E2). However, this …

An open label, comparative study of the effects of a dose-reduced oral contraceptive containing 20 μg ethinyl estradiol and 100 μg levonorgestrel on hemostatic, lipids …

J Endrikat, C Klipping, M Cronin, C Gerlinger, A Ruebig… - Contraception, 2002 - Elsevier
In this open label, randomized study we compared the influence of a dose-reduced oral
contraceptive containing 20 μg ethinyl estradiol (EE) and 100 μg levonorgestrel (20 EE) with …

A 1-year randomized study to evaluate the effects of a dose reduction in oral contraceptives on lipids and carbohydrate metabolism: 20 μg ethinyl estradiol combined …

SO Skouby, J Endrikat, B Düsterberg, W Schmidt… - Contraception, 2005 - Elsevier
OBJECTIVES: To evaluate the impact on lipid and carbohydrate variables of a combined
one-third ethinyl estradiol (EE)/levonorgestrel (LNG) dose reduction in oral contraceptives …

A pharmacokinetic study with a low-dose oral contraceptive containing 20 μg ethinylestradiol plus 100 μg levonorgestrel

J Endrikat, H Blode, C Gerlinger… - … European Journal of …, 2002 - Taylor & Francis
This study investigated the pharmacokinetics of a dose-reduced oral contraceptive
containing 20 μg ethinylestradiol (EE)+ 100 μg levonorgestrel (LNG) in 18 young, healthy …

A meta-analysis on the correlation between ovarian activity and the incidence of intermenstrual bleeding during low-dose oral contraceptive use

J Endrikat, C Gerlinger, K Plettig, J Wessel… - Gynecological …, 2003 - Taylor & Francis
We aimed to evaluate potential correlation between ovarian activity during use of combined
oral contraceptives and the incidence of intermenstrual bleeding. Data from seven …

A 3-year double-blind, randomized, controlled study on the influence of two oral contraceptives containing either 20 μg or 30 μg ethinylestradiol in combination with …

J Endrikat, E Mih, B Düsterberg, K Land, C Gerlinger… - Contraception, 2004 - Elsevier
In this first prospective, double-blind, randomized, parallel-group study we evaluated the
influence of two combined oral contraceptives on bone mineral density (BMD) and metabolic …

Combined ethinylestradiol/gestodene contraceptive patch: two-center, open-label study of ovulation inhibition, acceptability and safety over two cycles in female …

D Heger-Mahn, C Warlimont, T Faustmann… - … European Journal of …, 2004 - Taylor & Francis
Objectives Determination of the ovulation inhibition efficacy of a new, transparent,
transdermal, combined hormonal contraceptive patch (area 10 cm2) containing 0.9 mg …

Multicenter, comparative study of cycle control, efficacy and tolerability of two low-dose oral contraceptives containing 20 μg ethinylestradiol/100 μg levonorgestrel and …

J Endrikat, R Hite, R Bannemerschult, C Gerlinger… - Contraception, 2001 - Elsevier
A comparison of cycle control, efficacy and tolerability of two oral contraceptive preparations
containing 20 μg ethinylestradiol combined with either 100 μg levonorgestrel (EE/LNG …

Oral contraceptives containing 20 or 30 μg ethinylestradiol and 150 μg desogestrel: pharmacokinetics and pharmacodynamic parameters

C Jung-Hoffmann, M Fitzner, H Kuhl - Hormone Research in Paediatrics, 1991 - karger.com
The serum concentrations of ethinylestradiol (EE) and 3-keto-desogestrel (KDG) were
compared during treatment with a combination of 20 µg EE+ 150 µg DG (20EE/DG) or of 30 …