One of the classic hallmarks of cancer is the imbalance between elevated cell proliferation
and reduced cell death. Ceramide, a bioactive sphingolipid that can regulate this balance …

Beyond the wide use of tamoxifen in breast cancer chemotherapy due to its estrogen
receptor antagonist activity, this drug is being assayed in repurposing strategies against a …

Breast cancer is the most common cancer in women. Over the past few decades, advances
in cancer detection and treatment have significantly improved survival rate of breast cancer …

Background: Despite advancements in cancer treatment, breast cancer (BC) is still one of
the leading causes of death among women. The majority of anti-breast-cancer medications …

Tamoxifen is a selective estrogen receptor (ER) modulator that is used to treat ER-positive
breast cancer, but that at high doses kills both ER-positive and ER-negative breast cancer …

Breast cancer is a principal cause of cancer-related mortality in female worldwide. While
many approved therapies have shown promising outcomes in treating breast cancer …

The current experiments aimed to develop an anti-glioblastoma multiforme (GBM)
formulation based on rutin-loaded nanomicelles. First, the molecular structure of water, and …

Tamoxifen (TMX), commonly used in complementary therapy for breast cancer, also displays
known effects on the structure and function of biological membranes. This work presents an …

Only a few investigations, to our knowledge, have examined the bioenergetics of Tamoxifen
(TMX) resistant individuals and reported altered mitochondrial activity and metabolic profile …

The interaction of tamoxifen (TMX) and its metabolite 4-hydroxytamoxifen (HTMX) with a
biomimetic membrane model system composed of 1, 2-dielaidoylphosphatidylethanolamine …