The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness
Background The poor physical health of people with mental illness is a multifaceted,
transdiagnostic, and global problem. People with mental illness have an increased risk of …
transdiagnostic, and global problem. People with mental illness have an increased risk of …
Therapeutic potential of TAAR1 agonists in schizophrenia: evidence from preclinical models and clinical studies
Trace amine-associated receptor 1 (TAAR1) has emerged as a promising therapeutic target
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …
A comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study
Background Systematic reviews have consistently shown that individuals with mental
disorders have an increased risk of premature mortality. Traditionally, this evidence has …
disorders have an increased risk of premature mortality. Traditionally, this evidence has …
Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population‐based cohort study
The nature and prevalence of combinations of mental disorders and their associations with
premature mortality have never been reported in a comprehensive way. We describe the …
premature mortality have never been reported in a comprehensive way. We describe the …
Autoimmune diseases and psychotic disorders
R Jeppesen, ME Benros - Frontiers in Psychiatry, 2019 - frontiersin.org
The notion of immunological pathways playing a role in the etiology of a subset of psychotic
disorders has received increased interest in the last decades. One of the findings that has …
disorders has received increased interest in the last decades. One of the findings that has …
Clinical recovery and long-term association of specialized early intervention services vs treatment as usual among individuals with first-episode schizophrenia …
HG Hansen, M Starzer, SF Nilsson, C Hjorthøj… - JAMA …, 2023 - jamanetwork.com
Importance The OPUS 20-year follow-up is the longest follow-up of a randomized clinical
trial testing early intervention services (EIS) among individuals with first-episode …
trial testing early intervention services (EIS) among individuals with first-episode …
Cumulative burden of psychiatric disorders and self-harm across 26 adult cancers
WH Chang, AG Lai - Nature medicine, 2022 - nature.com
Cancer is a life-altering event causing considerable psychological distress. However,
information on the total burden of psychiatric disorders across all common adult cancers and …
information on the total burden of psychiatric disorders across all common adult cancers and …
[HTML][HTML] Life expectancy and years of potential life lost in people with mental disorders: a systematic review and meta-analysis
Background Mental disorders are associated with premature mortality. There is increasing
research examining life expectancy and years-of-potential-life-lost (YPLL) to quantify the …
research examining life expectancy and years-of-potential-life-lost (YPLL) to quantify the …
Shared genetic loci between body mass index and major psychiatric disorders: a genome-wide association study
S Bahrami, NE Steen, A Shadrin, K O'Connell… - JAMA …, 2020 - jamanetwork.com
Importance People with major psychiatric disorders (MPDs) have a 10-to 20-year shorter life
span than the rest of the population, and this difference is mainly due to comorbid …
span than the rest of the population, and this difference is mainly due to comorbid …
Longitudinal trends in childhood insulin levels and body mass index and associations with risks of psychosis and depression in young adults
Importance Cardiometabolic disorders often occur concomitantly with psychosis and
depression, contribute to high mortality rates, and are detectable from the onset of the …
depression, contribute to high mortality rates, and are detectable from the onset of the …