Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
Animal models of drug relapse and craving after voluntary abstinence: a review
Relapse to drug use during abstinence is a defining feature of addiction. During the last
several decades, this clinical scenario has been studied at the preclinical level using classic …
several decades, this clinical scenario has been studied at the preclinical level using classic …
Volitional social interaction prevents drug addiction in rat models
Addiction treatment has not been appreciably improved by neuroscientific research. One
problem is that mechanistic studies using rodent models do not incorporate volitional social …
problem is that mechanistic studies using rodent models do not incorporate volitional social …
Animal models of drug relapse and craving: from drug priming-induced reinstatement to incubation of craving after voluntary abstinence
High rates of relapse to drug use during abstinence is a defining feature of drug addiction. In
abstinent drug users, drug relapse is often precipitated by acute exposure to the self …
abstinent drug users, drug relapse is often precipitated by acute exposure to the self …
[HTML][HTML] Dopamine circuit mechanisms of addiction-like behaviors
CL Poisson, L Engel, BT Saunders - Frontiers in Neural Circuits, 2021 - frontiersin.org
Addiction is a complex disease that impacts millions of people around the world. Clinically,
addiction is formalized as substance use disorder (SUD), with three primary symptom …
addiction is formalized as substance use disorder (SUD), with three primary symptom …
[PDF][PDF] The anterior insular cortex→ central amygdala glutamatergic pathway is critical to relapse after contingency management
Despite decades of research on neurobiological mechanisms of psychostimulant addiction,
the only effective treatment for many addicts is contingency management, a behavioral …
the only effective treatment for many addicts is contingency management, a behavioral …
Operant social reward decreases incubation of heroin craving in male and female rats
Background We recently reported that operant social choice–induced voluntary abstinence
prevents incubation of methamphetamine craving. Here, we determined whether social …
prevents incubation of methamphetamine craving. Here, we determined whether social …
Role of dorsomedial striatum neuronal ensembles in incubation of methamphetamine craving after voluntary abstinence
D Caprioli, M Venniro, M Zhang… - Journal of …, 2017 - Soc Neuroscience
We recently developed a rat model of incubation of methamphetamine craving after choice-
based voluntary abstinence. Here, we studied the role of dorsolateral striatum (DLS) and …
based voluntary abstinence. Here, we studied the role of dorsolateral striatum (DLS) and …
[HTML][HTML] Incubation of methamphetamine but not heroin craving after voluntary abstinence in male and female rats
We recently introduced an animal model of incubation of methamphetamine craving after
choice-based voluntary abstinence in male rats. Here we studied the generality of this …
choice-based voluntary abstinence in male rats. Here we studied the generality of this …
In search of predictive endophenotypes in addiction: insights from preclinical research
Drug addiction is widely recognized to afflict some but not all individuals by virtue of
underlying risk markers and traits involving multifaceted interactions between polygenic and …
underlying risk markers and traits involving multifaceted interactions between polygenic and …