This study investigated the relationship between reinforcer value and choice between
cocaine and two non‐drug alternative reinforcers in rats. The essential value (EV, a …

Rationale and objectives Recent studies reported that when given a mutually exclusive
choice between cocaine and palatable food, most rats prefer the non-drug reward over …

We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after
food choice-induced voluntary abstinence. Here, we used this model to further study the role …

In rats trained to self‐administer methamphetamine, extinction responding in the presence of
drug‐associated contextual and discrete cues progressively increases after withdrawal …

In humans, reward cues, including drug cues in individuals experiencing addiction, are
especially effective in biasing attention towards them, so much so they can disrupt ongoing …

When facing a choice, most animals quit drugs in favour of a variety of nondrug alternatives.
We recently found, rather unexpectedly, that choice of the nondrug alternative is in fact …

To more effectively manage substance use disorders, it is imperative to understand the
neural, genetic, and psychological underpinnings of addictive behavior. To contribute to this …

The concept of compulsive cocaine-seeking habits is difficult to reconcile with other
evidence showing that humans and even rats remain able to shift their choice away from the …

Despite impressive results from neuroscience research using rodent models, there is a
paucity of successful translation from preclinical findings to effective pharmacological …

Rationale There are no FDA-approved treatments to facilitate recovery from cocaine use
disorder. Contingency management offers non-drug reinforcers to encourage abstinence …