Temperature is critical in regulating virtually all biological functions in fish. Low temperature
stress (cold shock/stress) is an often‐overlooked challenge that many fish face as a result of …

The hypoxia-inducible transcription factors are key regulators for the physiological response
to low oxygen availability. In vertebrates, typically three Hif-α isoforms, Hif-1α, Hif-2α and Hif …

Dissolved oxygen (DO) undountedly affects fish distribution, metabolism, and evern survival.
Intensive aquaculture and environmental changes will inevitably lead to hypoxic stress for …

The mechanisms by which phlebotomy promotes the mobilization of hepatic iron stores are
not well understood. NCOA4 (nuclear receptor coactivator 4) is a widely expressed …

Dissolved oxygen (DO) plays a crucial role in survival, growth, and normal physiological
functions of aquatic organisms. Nevertheless, the mechanisms involved in hypoxic stress …

As global climate changes, severely temperature variations have significant impacts on
survival and development of fish. While the potential effects of light wavelength on cold …

The first steps towards establishing xenografts in zebrafish embryos were performed by Lee
et al., 2005 and Haldi et al., 2006, paving the way for studying human cancers using this …

The need to better understand how plasticity and evolution affect organismal responses to
environmental variability is paramount in the face of global climate change. The potential for …

An organism's ability to respond effectively to environmental change is critical to its survival.
Yet, life stage and overall condition can dictate tolerance thresholds to heightened …

Tricaine, or MS-222, is the most commonly used chemical anesthetic in zebrafish research. It
is thought to act via blocking voltage-gated sodium channels, though its mechanism of …