Vascularization strategies in tissue engineering approaches for soft tissue repair

DS Masson‐Meyers, L Tayebi - Journal of tissue engineering …, 2021 - Wiley Online Library
Insufficient vascularization during tissue repair is often associated with poor clinical
outcomes. This is a concern especially when patients have critical‐sized injuries, where the …

New horizons of macrophage immunomodulation in the healing of diabetic foot ulcers

CW Lin, CM Hung, WJ Chen, JC Chen, WY Huang… - Pharmaceutics, 2022 - mdpi.com
Diabetic foot ulcers (DFUs) are one of the most costly and troublesome complications of
diabetes mellitus. The wound chronicity of DFUs remains the main challenge in the current …

Nanofiber-based systems intended for diabetes

H Maleki, K Khoshnevisan, SM Sajjadi-Jazi… - Journal of …, 2021 - Springer
Diabetic mellitus (DM) is the most communal metabolic disease resulting from a defect in
insulin secretion, causing hyperglycemia by promoting the progressive destruction of …

Wound healing potential of insulin-loaded nanoemulsion with Aloe vera gel in diabetic rats

T Chakraborty, S Gupta, A Nair, S Chauhan… - Journal of Drug Delivery …, 2021 - Elsevier
Diabetes skin infection is a very common disorder in hyperglycemic patients. This study
evaluated the prospective of developing a topical gel formulation of Aloe vera with insulin …

Antibacterial and wound healing activities of silver nanoparticles embedded in cellulose compared to other polysaccharides and protein polymers

M Alavi, RS Varma - Cellulose, 2021 - Springer
The aggregation of silver nanoparticles (AgNPs) in colloidal solution and the oxidative
cytotoxicity towards human cells are two major hindrances for their thriving medicinal …

[Retracted] Efficacy of Human Adipose Derived Mesenchymal Stem Cells in Promoting Skin Wound Healing

L Zhou, H Wang, S Yao, L Li… - Journal of Healthcare …, 2022 - Wiley Online Library
Background. The aim of this pilot clinical study is to evaluate the efficacy of human adipose
derived mesenchymal stem cells (HAMSCs) treatment for the wound healing with patients …

Topical insulin—utility and results in refractory neurotrophic keratopathy in stages 2 and 3

RJSM Soares, C Arêde, FS Neves… - Cornea, 2022 - journals.lww.com
Purpose: The purpose of this study was to evaluate the clinical outcome of patients with
refractory neurotrophic keratopathy (NK) in stages 2 and 3 treated with topical insulin …

Molecular mechanisms of skin wound healing in non-diabetic and diabetic mice in excision and pressure experimental wounds

VA Baldassarro, L Lorenzini, A Giuliani… - Cell and Tissue …, 2022 - Springer
Experimental models for chronic skin lesions are excision and pressure ulcer, defined as
“open” and “closed” lesions, respectively, only the latter characterized by tissue hypoxia …

The orchestra of human bacteriome by hormones

A Luqman - Microbial Pathogenesis, 2023 - Elsevier
Human microbiome interact reciprocally with the host. Recent findings showed the capability
of microorganisms to response towards host signaling molecules, such as hormones …

Three-layer sandwich-like drug-loaded nanofibers of insulin, titanium oxide Nanotubes and Nitroglycerin as a promising wound healing candidate

H Raei, M Jahanshahi, H Morad - Materials Chemistry and Physics, 2022 - Elsevier
In the human body, the skin is the first defensive layer against external pathogens, and all
injuries to the skin can be disastrous. Polymeric nanofibers have widely been used in most …