[HTML][HTML] The role of tumor microenvironment in regulating the plasticity of osteosarcoma cells

B Tian, X Du, S Zheng, Y Zhang - International Journal of Molecular …, 2022 - mdpi.com
Osteosarcoma (OS) is a malignancy that is becoming increasingly common in adolescents.
OS stem cells (OSCs) form a dynamic subset of OS cells that are responsible for malignant …

[HTML][HTML] Biological evidence of cancer stem-like cells and recurrent disease in osteosarcoma

C Jubelin, J Muñoz-Garcia, D Cochonneau… - Cancer Drug …, 2022 - ncbi.nlm.nih.gov
Sarcomas are a large family of cancers originating in the mesenchyme. Composed of more
than 100 histological subtypes, soft tissue and bone sarcomas remain clinically challenging …

Effect of P2X purinergic receptors in tumor progression and as a potential target for anti-tumor therapy

W Zhang - Purinergic Signalling, 2021 - Springer
The development of tumors is a complex pathological process involving multiple factors,
multiple steps, and multiple genes. Their prevention and treatment have always been a …

[HTML][HTML] Biochemical and cellular characterization of new radio-resistant cell lines reveals a role of natural flavonoids to bypass senescence

M Russo, C Spagnuolo, S Moccia, I Tedesco… - International Journal of …, 2021 - mdpi.com
Cancer is one of the main causes of death worldwide, and, among the most frequent cancer
types, osteosarcoma accounts for 56% of bone neoplasms observed in children and …

[HTML][HTML] Focus on hypoxia-related pathways in pediatric osteosarcomas and their druggability

M Pierrevelcin, Q Fuchs, B Lhermitte, M Messé… - Cells, 2020 - mdpi.com
Osteosarcoma is the most frequent primary bone tumor diagnosed during adolescence and
young adulthood. It is associated with the worst outcomes in the case of poor response to …

[HTML][HTML] Knockdown of STIP1 inhibits the invasion of CD133‑positive cancer stem‑like cells of the osteosarcoma MG63 cell line via the PI3K/Akt and ERK1/2 pathways

JH Wang, C Gong, FJ Guo, X Zhou… - International …, 2020 - spandidos-publications.com
Osteosarcoma is the most common primary malignant tumor of the bone in adolescents and
children, with high rates of metastasis and a poor prognosis. Recently, osteosarcoma cancer …

Marine seaweed endophytic fungi-derived active metabolites promote reactive oxygen species-induced cell cycle arrest and apoptosis in human breast cancer cells

J Venkatachalam, VS Jeyadoss, KSC Bose… - Molecular Biology …, 2024 - Springer
Background Endophytic fungi have an abundant sources rich source of rich bioactive
molecules with pivotal pharmacological properties. Several studies have found that …

[HTML][HTML] Anticancer effects and lysosomal acidification in A549 cells by Astaxanthin from Haematococcus lacustris

K Ramamoorthy, S Raghunandhakumar… - …, 2020 - ncbi.nlm.nih.gov
Astaxanthin (AXN) is known to have health benefits by epidemiological studies. Therefore, it
is of interest to assess the effect of AXN (derived from indigenous unicellular green alga …

Chelerythrine Inhibits Stemness of Cancer Stem‐Like Cells of Osteosarcoma and PI3K/AKT/mTOR Signal

Z Chen, H Yang, Q Zhang, Q Hu, Z Zhao - Journal of Oncology, 2022 - Wiley Online Library
Chelerythrine (CHE) is widely found in many herbs and is the main alkaloid constituent of
Toddalia asiatica (L.) LAM. It has been proved to exert remarkable antitumor, antifungal, anti …

ANTI PROLIFERATIVE ACTIVITY OF ANDROGRAPHIS PANICULATA WHOLE PLANT EXTRACT ON A549 LUNG CANCER CELL LINE.

Y Guntupalli, S Raghunandhakumar… - … Journal of Early …, 2022 - search.ebscohost.com
Introduction: Lung cancer is one of the most common forms of cancer in the world. Cases are
increasing globally everyday mainly due to increased habits of tobacco smoking. Timely …