It is one of the central aims of the philosophy of science to elucidate the meanings of
scientific terms and also to think critically about their application. The focus of this essay is …

The dimethyhydrazine (DMH) or azoxymethane (AOM) model is a well-established, well-
appreciated, and widely used model of experimental colon carcinogenesis. It has many …

Systematic reviews are currently favored methods of evaluating research in order to reach
conclusions regarding medical practice. The need for such reviews is necessitated by the …

The aim of this review is to provide a thorough overview of the health effects from the
complexed biomagnified mixture of long-range transported industrial organochlorines …

This chapter provides an introduction to the concept of laboratory animal models, focusing
on a general classification of animal models for the study of human diseases. Animal models …

The central concern of this book is with the" prediction problem" in biomedical research. In
particular, the authors examine the use of animal models to predict human responses in …

We surveyed the scientific literature regarding amyotrophic lateral sclerosis, the SOD1
mouse model, complex adaptive systems, evolution, drug development, animal models, and …

Background: The propensity for bacterial localization within bones of juvenile pigs is similar
to the situation in humans, where haematogenously based osteomyelitis most commonly …

Every year, and in countries around the world, significant time and resources are devoted to
the noble cause of developing drugs to treat and cure human disease. With rare exception …

Cerebral white matter lesion (WML) is one of the main causes for cognitive impairment and
is often caused by chronic cerebral hypoperfusion. A line of evidence has shown that aspirin …