Abdominal aortic aneurysm: roles of inflammatory cells
Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
The mechanism and therapy of aortic aneurysms
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
Monocytes and macrophages in abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
Understanding the pathogenesis of abdominal aortic aneurysms
An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …
the aortic wall continues to weaken and becomes unable to withstand the forces of the …
Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …
mediated infiltration and a destruction of the aortic wall during AAA development plays …
AAA revisited: a comprehensive review of risk factors, management, and hallmarks of pathogenesis
V Kessler, J Klopf, W Eilenberg, C Neumayer… - Biomedicines, 2022 - mdpi.com
Despite declining incidence and mortality rates in many countries, the abdominal aortic
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms
FM Davis, LC Tsoi, WJ Melvin, A DenDekker… - Journal of Experimental …, 2021 - rupress.org
Abdominal aortic aneurysms (AAAs) are a life-threatening disease for which there is a lack
of effective therapy preventing aortic rupture. During AAA formation, pathological vascular …
of effective therapy preventing aortic rupture. During AAA formation, pathological vascular …
Novel role of IL (Interleukin)-1β in neutrophil extracellular trap formation and abdominal aortic aneurysms
AK Meher, M Spinosa, JP Davis, N Pope… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Neutrophils promote experimental abdominal aortic aneurysm (AAA) formation
via a mechanism that is independent from MMPs (matrix metalloproteinases). Recently, we …
via a mechanism that is independent from MMPs (matrix metalloproteinases). Recently, we …
Matrix metalloproteinase in abdominal aortic aneurysm and aortic dissection
Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD)
is a life-threatening aortic pathology associated with high morbidity and mortality. Initiators of …
is a life-threatening aortic pathology associated with high morbidity and mortality. Initiators of …
Circular RNA Cdyl promotes abdominal aortic aneurysm formation by inducing M1 macrophage polarization and M1-type inflammation
H Song, Y Yang, Y Sun, G Wei, H Zheng, Y Chen… - Molecular Therapy, 2022 - cell.com
Macrophage polarization plays a crucial role in regulating abdominal aortic aneurysm (AAA)
formation. Circular RNAs (circRNAs) are important regulators of macrophage polarization …
formation. Circular RNAs (circRNAs) are important regulators of macrophage polarization …