In the past decade, numerous studies have demonstrated the close relationship between gut
microbiota and the occurrence and development of Alzheimer's disease (AD). However, the …

Tauroursodeoxycholic acid (TUDCA) is a naturally occurring hydrophilic bile acid that has
been used for centuries in Chinese medicine. Chemically, TUDCA is a taurine conjugate of …

Bile acids are steroid acids found in the bile of mammals. The bile acid conjugate
tauroursodeoxycholic acid (TUDCA) is neuroprotective in different animal models of stroke …

Next‐generation neural interfaces for bidirectional communication with the central nervous
system aim to achieve the intimate integration with the neural tissue with minimal …

The human gut microbiome has been linked to numerous digestive disorders, but its
metabolic products have been much less well characterized, in part due to the expense of …

Bile acids (BA) are important physiological molecules not only mediating nutrients
absorption and metabolism in peripheral tissues, but exerting neuromodulation effect in the …

Parkinson's disease (PD) is characterized by severe motor symptoms, and currently there is
no treatment that retards disease progression or reverses damage prior to the time of clinical …

Objective: Parkinson's disease (PD) is a progressive motor disease of unknown etiology.
Although neuroprotective ability of endogenous bile acid, tauroursodeoxycholic acid …

Traumatic brain injury (TBI) is one of the leading causes of trauma-induced mortality and
disability, and emerging studies have shown that endoplasmic reticulum (ER) stress plays …

Gut microbiota have crucial effects on brain function via the gut-brain axis. Growing
evidence suggests that this interaction is mediated by signaling molecules derived from …