[HTML][HTML] The T cell immune response against SARS-CoV-2
P Moss - Nature immunology, 2022 - nature.com
The adaptive immune response is a major determinant of the clinical outcome after SARS-
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …
[HTML][HTML] T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
[HTML][HTML] Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers
Abstract PD-1 blockade unleashes CD8 T cells, including those specific for mutation-
associated neoantigens (MANA), but factors in the tumour microenvironment can inhibit …
associated neoantigens (MANA), but factors in the tumour microenvironment can inhibit …
[HTML][HTML] The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses
Pre-existing cross-reactive immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …
[HTML][HTML] SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans
SARS-CoV-2 mRNA vaccines induce robust anti-spike (S) antibody and CD4+ T cell
responses. It is not yet clear whether vaccine-induced follicular helper CD4+ T (T FH) cell …
responses. It is not yet clear whether vaccine-induced follicular helper CD4+ T (T FH) cell …
[HTML][HTML] Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
[HTML][HTML] Establishment and recall of SARS-CoV-2 spike epitope-specific CD4+ T cell memory
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination
elicit CD4+ T cell responses to the spike protein, including circulating follicular helper T …
elicit CD4+ T cell responses to the spike protein, including circulating follicular helper T …
[HTML][HTML] Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice
RP dos Santos Alves, J Timis, R Miller… - Nature …, 2024 - nature.com
Abstract SARS-CoV-2-reactive T cells are detected in some healthy unexposed individuals.
Human studies indicate these T cells could be elicited by the common cold coronavirus …
Human studies indicate these T cells could be elicited by the common cold coronavirus …
[HTML][HTML] T cell immunity to SARS-CoV-2
Exceptional efforts have been undertaken to shed light into the biology of adaptive immune
responses to SARS-CoV-2. T cells occupy a central role in adaptive immunity to mediate …
responses to SARS-CoV-2. T cells occupy a central role in adaptive immunity to mediate …
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens
The baseline composition of T cells directly affects later response to pathogens, but the
complexity of precursor states remains poorly defined. Here, we examined the baseline state …
complexity of precursor states remains poorly defined. Here, we examined the baseline state …