目的探讨Rho 相关卷曲螺旋形成蛋白激酶(ROCK) 1 和ROCK2 对急性ST 段抬高型心肌梗死(
STEMI) 患者经皮冠状动脉介入治疗(PCI) 无复流的预测价值. 方法选取168 例接受PCI 的STEMI …

Increasing evidences have illustrated the important role of N6-methyladenosine (m6A) in
atherosclerosis (AS). However, the role of m6A modification in AS pathophysiological …

Traumatic brain injury (TBI) is the leading cause of injury-induced disabilities that decrease
quality of life. Neuroinflammation propagated by immune cells like microglia causes or …

Loss of podocytes is a common feature of diabetic renal injury and a key contributor to the
development of albuminuria. We found that podocyte Rho associated coiled-coil containing …

Severe COVID-19 is characterized by acute respiratory distress syndrome (ARDS)-like
hyperinflammation and endothelial dysfunction, that can lead to respiratory and multi organ …

Primary cilia are microtubule-based organelles that act as cellular antennae to mediate
vertebrate development and growth factor signalling. Defects in primary cilia result in a …

Nas últimas décadas, diversos estudos demonstraram a importante ação anti-inflamatória
da CTX, avaliada diretamente sobre funções de neutrófilos e macrófagos, além do seu …

Increasing evidence illustrates the important roles of N 6-methyladenosine (m 6 A) in
progression of atherosclerosis (AS). However, the connections between m 6 A modification …

Single nucleotide polymorphisms in the gene encoding G protein-coupled receptor 35
(GPR35) are associated with increased risk of inflammatory bowel disease. However, the …

Rho-associated coiled coil-containing protein kinases (ROCK) are downstream effectors of
the RhoA GTPase, and have 2 known isoforms (ROCK1 and ROCK2). Nonselective ROCK …