Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives

A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …

[HTML][HTML] Generation and testing of clinical-grade exosomes for pancreatic cancer

M Mendt, S Kamerkar, H Sugimoto, KM McAndrews… - JCI insight, 2018 - ncbi.nlm.nih.gov
Exosomes are extracellular vesicles produced by all cells with a remarkable ability to
efficiently transfer genetic material, including exogenously loaded siRNA, to cancer cells …

Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Extracellular vesicle heterogeneity and its impact for regenerative medicine applications

SI van de Wakker, FM Meijers, JPG Sluijter… - Pharmacological …, 2023 - ASPET
Extracellular vesicles (EVs) are cell-derived membrane-enclosed particles that are involved
in physiologic and pathologic processes. EVs are increasingly being studied for therapeutic …

[HTML][HTML] Engineering exosome-based biomimetic nanovehicles for wound healing

A Joorabloo, T Liu - Journal of Controlled Release, 2023 - Elsevier
Complexity and difficulties in wound management are pressing concerns that affect patients'
quality of life and may result in tissue infection, necrosis, and loss of local and systemic …

The distinct roles of exosomes in innate immune responses and therapeutic applications in cancer

J Rezaie, T Etemadi, M Feghhi - European journal of pharmacology, 2022 - Elsevier
The innate immune system is one of the major constituents of the host's defense against
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …

Exosomes as biomarkers for female reproductive diseases diagnosis and therapy

S Esfandyari, H Elkafas, RM Chugh, H Park… - International journal of …, 2021 - mdpi.com
Cell–cell communication is an essential mechanism for the maintenance and development
of various organs, including the female reproductive system. Today, it is well-known that the …

Comparative proteomic analysis of exosomes and microvesicles in human saliva for lung cancer

Y Sun, C Huo, Z Qiao, Z Shang… - Journal of proteome …, 2018 - ACS Publications
Extracellular vesicles (EVs) are cell-derived microparticles present in most body fluids,
mainly including microvesicles and exosomes. EV-harbored proteins have emerged as …

[HTML][HTML] Bioglass enhances the production of exosomes and improves their capability of promoting vascularization

Z Wu, D He, H Li - Bioactive Materials, 2021 - Elsevier
Recently, exosomes have been extensively applied in tissue regeneration. However, their
practical applications are severely restricted by the limited exosome secretion capability of …