Although acute itch has a protective role by removing irritants to avoid further damage,
chronic itch is debilitating, significantly impacting quality of life. Over the past two decades, a …

Background Although the cytokine IL-31 has been implicated in inflammatory and lymphoma-
associated itch, the cellular basis for its pruritic action is yet unclear. Objective We sought to …

Cutaneous T‐cell lymphomas (CTCLs) have a chronic, relapsing course, and the most
common subtypes are mycosis fungoides and Sézary syndrome. The disease causes visible …

Chronic itch is a major symptom of many inflammatory skin diseases. This type of pruritus is
thought to be facilitated by cytokines that activate cutaneous nerve fibers; however, the …

Cutaneous T-cell lymphomas (CTCL) are a heterogenous group of non-Hodgkin's
lymphomas of skin-trafficking T lymphocytes (Diamandidou et al., 1996). CTCL patients often …

Cutaneous lymphomas (CL) are categorized as extranodal non-Hodgkin lymphomas,
constituting the second most common form in this group (MALT lymphomas of the stomach …

Approximately 88% of cutaneous T-cell lymphoma (CTCL) patients are affected by pruritus
that responds poorly to current antipruritic therapies. Interleukin (IL)-31, a Th2 cytokine, has …

Cutaneous T-cell lymphoma is a heterogeneous group of lymphomas characterized by the
accumulation of malignant T cells in the skin. The molecular and cellular etiology of this …

S2k-Leitlinie - Kutane Lymphome (ICD10 C82-C86): Update 2021 S2k-Leitlinie - Kutane
Lymphome (ICD10 C82-C86): Update 2021 J Dtsch Dermatol Ges. 2022 Apr;20(4):537-555 …

Chronic pruritus (CP) has considerable implications for QOL. However, its impact on health-
related QOL and economic burden is not fully characterized. We administered a cross …