The epithelia that line the conducting airways are the lung's first point of contact with inhaled
pathogens and toxicants. As such, they are known to play an important role in the lung's …

Multidrug resistance (MDR) by bacterial pathogens constitutes a global health crisis, and
resistance to treatment displayed by biofilm-associated infections (eg, cystic fibrosis, surgical …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that affects
approximately 1/68 children, with a more recent study suggesting numbers as high as 1/36 …

The pH of airway epithelial secretions influences bacterial killing and mucus properties and
is reduced by acidic pollutants, gastric reflux, and respiratory diseases such as cystic fibrosis …

Acidic microenvironments commonly occur at sites of inflammation and bacterial infections.
In the context of a Pseudomonas aeruginosa infection, we previously demonstrated that …

BPI fold containing family A, member 1 (BPIFA1) and BPIFB1 are putative innate immune
molecules expressed in the upper airways. Because of their hypothesized roles in airway …

Respiratory failure, driven by airways mucus obstruction, chronic inflammation and bacterial
infections, is the main cause of mortality and morbidity in people with cystic fibrosis (CF) due …

In the present work, microgels were utilized as a cell-free reaction environment to produce a
functional malonyl-CoA synthetase (deGFP-MatB) under geometry-controlled transcription …

Introduction: Cystic fibrosis (CF) is caused by defective Cystic Fibrosis Transmembrane
Conductance Regulator (CFTR) proteins. CFTR controls chloride (Cl−) and bicarbonate …

Cystic fibrosis (CF) is a lethal inherited disease produced by mutations in the gene encoding
the CFTR chloride channel. Loss of function in the CFTR gene is associated with a not much …