Sirt3-Sod2-mROS-mediated manganese triggered hepatic mitochondrial dysfunction and lipotoxicity in a freshwater teleost

T Zhao, WH Lv, C Hogstrand, DG Zhang… - Environmental …, 2022 - ACS Publications
Exposure to excessive manganese (Mn) is toxic to humans and animals. However, the toxic
effects and mechanisms of excessive Mn influencing the vertebrates have been highly …

Independent and combined associations of blood manganese, cadmium and Lead exposures with the systemic immune-inflammation index in adults

Q Zhong, W Zhou, J Lin, W Sun, Y Qin, X Li, H Xu - Toxics, 2023 - mdpi.com
Manganese (Mn), cadmium (Cd) and lead (Pb) have toxic effects on the immune system.
However, their independent and combined effects on immune-inflammation responses are …

Effect of long-term manganese exposure on oxidative stress, liver damage and apoptosis in grouper Epinephelus moara♀× Epinephelus lanceolatus♂

X Wang, BL Liu, XQ Gao, YY Fang… - Frontiers in Marine …, 2022 - frontiersin.org
Manganese (Mn) is an indispensable trace element, however, it may occur at high
concentrations in water and sediments of aquatic ecosystems due to natural and …

Identification of histone acetylation modification sites in the striatum of subchronically manganese-exposed rats

C Ao, S Tang, Y Yang, Y Liu, H Zhao, J Ban, J Li - Epigenomics, 2024 - Future Medicine
Aim: To explore the specific histone acetylation sites and oxidative stress-related genes that
are associated with the pathogenesis of manganese toxicity. Methods: We employed liquid …

High water temperature-mediated immune gene expression of olive flounder, Paralichthys olivaceus according to pre-stimulation at high temperatures

D Lee, KH Kim, JW Park, JH Lee, JH Kim - Environmental Toxicology and …, 2023 - Elsevier
Increased ocean temperature due to global warming affects the health and immunity of fish.
In this study, juvenile Paralichthys olivaceus were exposed to high temperature after pre …

Investigation of oxidative stress status and apoptotic markers of juvenile trout exposed to arsenic toxicity

H Saç, AÇ Yeltekin - Toxicology Research, 2023 - academic.oup.com
Arsenic is one of the most abundant elements on earth. Arsenic, also called metalloid, is
used as a raw material in many industries. Arsenic causes the acceleration of free radical …

Associations of multiple metals exposure with immunoglobulin levels in pregnant women: Hangzhou Birth Cohort Study

J Zhou, L Jin, Y Zhou, K Zhong, K Huang… - Journal of …, 2025 - Elsevier
Metal may affect maternal immune function, but few epidemiological studies have reported
the associations between multiple-metal exposure and maternal immunoglobulin (Ig) levels …

Exposure to manganese (II) chloride induces developmental toxicity, oxidative stress and inflammatory response in Marine medaka (Oryzias melastigma) embryos

K Liu, D Yu, M Xin, F Lü, Z Zhang, J Zhou, T Liu, X Liu… - Aquatic Toxicology, 2023 - Elsevier
Manganese (Mn) is an essential metal for organisms, but high levels can induce serious
toxicity. To date, the toxic mechanism of Mn to marine fish is still poorly understood. In the …

Multiple biomarkers response of Astyanax lacustris (Teleostei: Characidae) exposed to manganese and temperature increase

KG Gnocchi, J Boldrini-França, LS Passos… - Environmental …, 2023 - Elsevier
The present study aimed to evaluate the toxicity of Mn (6.65 mg/L) at different exposure
times (96 h, 7, 14, and 21 days) and evaluate its possible toxic effects on the fish Astyanax …

Integrating reverse osmosis to a conventional river water treatment plant as a strategy to produce drinking water after mining dam rupture events: a case study

VR Moreira, PB Moser, RN Guimarães… - Environmental …, 2024 - Taylor & Francis
Incidents of mining dam failure have compromised the water quality, threatening the water
supply. Different strategies are sought to restore the impacted area and to guarantee the …