Gene-edited natural killer cells

V Sluch, A Rezania, J Sagert, D Swain - US Patent 11,591,381, 2023 - Google Patents
US11591381B2 - Gene-edited natural killer cells - Google Patents US11591381B2 - Gene-edited
natural killer cells - Google Patents Gene-edited natural killer cells Download PDF Info …

Chimeric antigen receptor system with adaptable receptor specificity

JM Carton, MF Naso, LG Borges, J Wheeler… - US Patent …, 2024 - Google Patents
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl) anilino] pyrimidin-4-yl]
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …

Artificial cell death polypeptide for chimeric antigen receptor and uses thereof

M Naso, J Carton, J Wheeler, L Borges - US Patent 11,661,459, 2023 - Google Patents
US11661459B2 - Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
- Google Patents US11661459B2 - Artificial cell death polypeptide for chimeric antigen receptor …

Gene-edited natural killer cells

V Sluch, A Rezania, J Sagert - US Patent 11,459,372, 2022 - Google Patents
The present invention relates to, inter alia, an engineered cell (eg, iPSC, IPS-derived NK, or
NK cell) comprising a disrupted B2M gene and an inserted polynucleotide encoding one or …

Universal donor cells

A Rezania, V Sluch - US Patent 11,566,230, 2023 - Google Patents
VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC (= O) CC
[C@ H](N) C (= O) N [C@@ H](C) C (= O) N [C@@ H](CCC (O)= O) C (= O) N [C@@ H](CC …

Universal donor cells

A Rezania, V Sluch - US Patent 11,578,309, 2023 - Google Patents
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …