Bayesian network meta-analysis of randomized controlled trials on the efficacy of antiarrhythmics in the pharmacological cardioversion of paroxysmal atrial fibrillation

D Orso, S Santangelo, N Guglielmo, T Bove… - American Journal of …, 2023 - Springer
Purpose Since atrial fibrillation (AF) is one of the major arrhythmias managed in hospitals
worldwide, it has a major impact on public health. The guidelines agree on the desirability of …

Pharmacologic cardioversion in patients with paroxysmal atrial fibrillation: a network meta-analysis

D Tsiachris, I Doundoulakis, E Pagkalidou… - … drugs and therapy, 2021 - Springer
Purpose We sought to indirectly compare and rank antiarrhythmic agents focusing
exclusively on adults with paroxysmal atrial fibrillation in order to identify the most effective …

Real-world utilization of the pill-in-the-pocket method for terminating episodes of atrial fibrillation: data from the multinational Antiarrhythmic Interventions for Managing …

JA Reiffel, C Blomström-Lundqvist, G Boriani… - Europace, 2023 - academic.oup.com
Aims Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical
practice. Episodes may stop spontaneously (paroxysmal AF); may terminate only via …

Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network …

IS Desouza, P Shrestha, R Allen, J Koos… - … Drugs and Therapy, 2024 - Springer
Purpose The available evidence to determine which antidysrhythmic drug is superior for
pharmacologic cardioversion of recent-onset (onset within 48 h) atrial fibrillation (AF) is …

[HTML][HTML] Investigational Anti–Atrial Fibrillation Pharmacology and Mechanisms by Which Antiarrhythmics Terminate the Arrhythmia: Where Are We in 2020?

A Burashnikov - Journal of Cardiovascular Pharmacology, 2020 - journals.lww.com
Antiarrhythmic drugs remain the mainstay therapy for patients with atrial fibrillation (AF). A
major disadvantage of the currently available anti-AF agents is the risk of induction of …

[HTML][HTML] How to optimize cardioversion of atrial fibrillation

KEJ Airaksinen - Journal of Clinical Medicine, 2022 - mdpi.com
Cardioversion (CV) is an essential component of rhythm control strategy in the treatment of
atrial fibrillation (AF). Timing of CV is an important manageable factor in optimizing the safety …

[HTML][HTML] Acute Management of Paroxysmal Atrial Fibrillation with Intravenous Flecainide plus Oral Beta-Blockers

A Kartalis, D Afendoulis, P Voutas, M Moutafi… - International Journal of …, 2024 - mdpi.com
Background: Intravenous (IV) flecainide is recommended for the pharmacological
cardioversion of recent-onset atrial fibrillation (AF). The aim of this study was to study the …

[HTML][HTML] Effect of Early Pharmacologic Cardioversion vs. Non-early Cardioversion in the Patients With Recent-Onset Atrial Fibrillation Within 4-Week Follow-Up Period …

Y Tang, Y Wang, X Sun, Y Shi, S Liu… - Frontiers in …, 2022 - frontiersin.org
Background Whether early pharmacologic cardioversion is necessary for recent-onset atrial
fibrillation is still controversial. Current meta-analyses were limited to evaluating the effects …

[HTML][HTML] The efficacy and safety of amiodarone combined with beta-blockers in the maintenance of sinus rhythm for atrial fibrillation: A protocol for systematic review …

S Shi, Q Jia, J Shi, S Shi, G Yuan, Y Hu - Medicine, 2020 - journals.lww.com
Background: The high recurrence rate of atrial fibrillation (AF) after recovering sinus rhythm
has always been a clinical problem. Despite the established and widespread use of …

New methodological approaches to atrial fibrillation drug discovery

CK Wong, HF Tse - Expert Opinion on Drug Discovery, 2021 - Taylor & Francis
Introduction Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical
practice and rhythm control using pharmacological agents is required in selected patients …