Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

Flavonoids: an overview

AN Panche, AD Diwan, SR Chandra - Journal of nutritional science, 2016 - cambridge.org
Flavonoids, a group of natural substances with variable phenolic structures, are found in
fruits, vegetables, grains, bark, roots, stems, flowers, tea and wine. These natural products …

Oxidative stress in angiogenesis and vascular disease

YW Kim, TV Byzova - Blood, the Journal of the American …, 2014 - ashpublications.org
Despite the damaging effect on tissues at a high concentration, it has been gradually
established that oxidative stress plays a positive role during angiogenesis. In adults …

[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy

Z Wang, C Dabrosin, X Yin, MM Fuster, A Arreola… - Seminars in cancer …, 2015 - Elsevier
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

[HTML][HTML] Cytotoxicity of dietary flavonoids on different human cancer types

K Sak - Pharmacognosy reviews, 2014 - ncbi.nlm.nih.gov
Flavonoids are ubiquitous in nature. They are also in food, providing an essential link
between diet and prevention of chronic diseases including cancer. Anticancer effects of …

Anti-cancer potential of flavonoids: recent trends and future perspectives

P Batra, AK Sharma - 3 Biotech, 2013 - Springer
Cancer is a major public health concern in both developed and developing countries.
Several plant-derived anti-cancer agents including taxol, vinblastine, vincristine, the …

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

E Middleton, C Kandaswami, TC Theoharides - Pharmacological reviews, 2000 - ASPET
Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible
for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil …

[HTML][HTML] Flavonoids: a review of probable mechanisms of action and potential applications

RJ Nijveldt, ELS Van Nood, DEC Van Hoorn… - The American journal of …, 2001 - Elsevier
The aim of this review, a summary of the putative biological actions of flavonoids, was to
obtain a further understanding of the reported beneficial health effects of these substances …

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β

GGJM Kuiper, JG Lemmen, BO Carlsson… - …, 1998 - academic.oup.com
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ,
which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation …

The biochemistry and medical significance of the flavonoids

BH Havsteen - Pharmacology & therapeutics, 2002 - Elsevier
Flavonoids are plant pigments that are synthesised from phenylalanine, generally display
marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are …