Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways

K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Bioactive peptides from muscle sources: meat and fish

JT Ryan, RP Ross, D Bolton, GF Fitzgerald, C Stanton - Nutrients, 2011 - mdpi.com
Bioactive peptides have been identified in a range of foods, including plant, milk and
muscle, eg, beef, chicken, pork and fish muscle proteins. Bioactive peptides from food …

[HTML][HTML] Empagliflozin and progression of kidney disease in type 2 diabetes

C Wanner, SE Inzucchi, JM Lachin… - … England Journal of …, 2016 - Mass Medical Soc
Background Diabetes confers an increased risk of adverse cardiovascular and renal events.
In the EMPA-REG OUTCOME trial, empagliflozin, a sodium–glucose cotransporter 2 …

2018 Korean Society of Hypertension Guidelines for the management of hypertension: part II-diagnosis and treatment of hypertension

HY Lee, J Shin, GH Kim, S Park, SH Ihm, HC Kim… - Clinical …, 2019 - Springer
The standardized techniques of blood pressure (BP) measurement in the clinic are
emphasized and it is recommended to replace the mercury sphygmomanometer by a non …

Functional foods and nutraceuticals as dietary intervention in chronic diseases; novel perspectives for health promotion and disease prevention

SA Adefegha - Journal of dietary supplements, 2018 - Taylor & Francis
Functional foods describe the importance of foods in promoting health and preventing
diseases aside their primary role of providing the body with the required amount of essential …

Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial—the Losartan Heart Failure Survival Study ELITE II

B Pitt, PA Poole-Wilson, R Segal, FA Martinez… - The Lancet, 2000 - thelancet.com
Background The ELITE study showed an association between the angiotensin II antagonist
losartan and an unexpected survival benefit in elderly heart-failure patients, compared with …

Discovery and characterization of smORF-encoded bioactive polypeptides

A Saghatelian, JP Couso - Nature chemical biology, 2015 - nature.com
Abstract Analysis of genomes, transcriptomes and proteomes reveals the existence of
hundreds to thousands of translated, yet non-annotated, short open reading frames (small …

[HTML][HTML] Hypotensive peptides from milk proteins

RJ FitzGerald, BA Murray, DJ Walsh - The Journal of nutrition, 2004 - Elsevier
Hypertension is the major controllable risk factor associated with cardiovascular disease
(CVD) events such as myocardial infarction, stroke, heart failure, and end-stage diabetes. A …

Molecular mechanisms of obesity-linked cardiac dysfunction: an up-date on current knowledge

J Gutiérrez-Cuevas, A Sandoval-Rodriguez… - Cells, 2021 - mdpi.com
Obesity is defined as excessive body fat accumulation, and worldwide obesity has nearly
tripled since 1975. Excess of free fatty acids (FFAs) and triglycerides in obese individuals …

[HTML][HTML] Angiotensin-receptor blockade versus converting–enzyme inhibition in type 2 diabetes and nephropathy

AH Barnett, SC Bain, P Bouter, B Karlberg… - … England Journal of …, 2004 - Mass Medical Soc
Background Few studies have directly compared the renoprotective effects of angiotensin II–
receptor blockers and angiotensin-converting–enzyme (ACE) inhibitors in persons with type …