Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats
C Aranäs, CE Edvardsson, OT Shevchouk, Q Zhang… - …, 2023 - thelancet.com
Background Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce
alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD) …
alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD) …
Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents
S Witley, CE Edvardsson, C Aranäs… - Translational …, 2024 - nature.com
The mechanisms contributing to alcohol use disorder (AUD) are complex and the orexigenic
peptide ghrelin, which enhances alcohol reward, is implied as a crucial modulator. The …
peptide ghrelin, which enhances alcohol reward, is implied as a crucial modulator. The …
Antismoking agents do not contribute synergistically to semaglutide's ability to reduce alcohol intake in rats
C Aranäs, S Blid Sköldheden, E Jerlhag - Frontiers in Pharmacology, 2023 - frontiersin.org
Preclinical studies have identified glucagon-like peptide-1 receptor (GLP-1R) agonists, and
the antismoking agents varenicline and bupropion as tentative agents for treatment of …
the antismoking agents varenicline and bupropion as tentative agents for treatment of …
[HTML][HTML] Decoding the influence of central LEAP2 on food intake and its effect on accumbal dopamine release
M Tufvesson-Alm, Q Zhang, C Aranäs… - Progress in …, 2024 - Elsevier
The gut-brain peptide ghrelin and its receptor are established as a regulator of hunger and
reward-processing. However, the recently recognized ghrelin receptor inverse agonist, liver …
reward-processing. However, the recently recognized ghrelin receptor inverse agonist, liver …
Decoding the influence of central LEAP2 on hedonic food intake and its association with dopaminergic reward pathways
M Tufvesson-Alm, Q Zhang, C Aranäs… - bioRxiv, 2023 - biorxiv.org
The gut-brain peptide ghrelin and its receptor (GHSR) are established as a regulator of
hunger and reward-processing. However, the recently recognized GHSR inverse agonist …
hunger and reward-processing. However, the recently recognized GHSR inverse agonist …
[PDF][PDF] Is There a Natural, Non-Addictive, And Non-Anti-Reward, Safe, Gene-Based Solution to Treat Reward Deficiency Syndrome (RDS)? KB220 Variants Vs. GLP-1 …
Abstract Reward Deficiency Syndrome (RDS) is an umbrella term encompassing a wide
array of addictive behaviors that affect individuals across diverse spectra of society. Our …
array of addictive behaviors that affect individuals across diverse spectra of society. Our …