Type 2 diabetes is characterized by insulin resistance and loss of β cell mass and function.
Aging is considered as a major risk factor for development of type 2 diabetes. However, the …

The distinct biology of pancreatic cancer with aggressive and early invasive tumor cells, a
tumor promoting microenvironment, late diagnosis, and high therapy resistance poses major …

Digestive system diseases arise primarily through the interplay of genetic and environmental
influences; there is an urgent need in elucidating the pathogenic mechanisms of these …

Although it is well established that diabetes can also develop as a result of diseases or
maneuvers on the exocrine pancreas, the complex relationship between glucose disorders …

An increasing number of studies have demonstrated that disease states of the endocrine or
exocrine pancreas aggravate one another, which implies bidirectional blood flow between …

Diabetes mellitus is a global disease requiring long-term treatment and monitoring. At
present, pancreas or islet transplantation is the only reliable treatment for achieving stable …

Pancreatic cancer (PC) is one of the most lethal cancers and 12th most common cancer in
the world. Due to the inaccessible anatomical position of the pancreas and asymptomatic …

Background To investigate the clinical significance of preoperative inflammatory status in
patients with pancreatic head carcinoma (PHC), we performed a single-center study to …

Arginine vasopressin (AVP), a peptide secreted from the posterior pituitary, is chiefly
regarded as a hormone involved in the regulation of body fluid balance and osmolality …

Pancreatic tumors are classified into endocrine and exocrine types, and the clinical
manifestations in patients are nonspecific. Most patients, especially those with pancreatic …