BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …

Highlights•Photoacoustic tomography is capable of molecular imaging with high spatial
resolution and deep penetration depth.•Recent advances in PAT system have made …

It is generally considered that photoacoustic imaging (PAI) and fluorescence imaging (FLI)
cannot be enhanced concurrently, as they are dependent on competitive photophysical …

Lipid deposition inside the arterial wall is a key indicator of plaque vulnerability. An
intravascular photoacoustic (IVPA) catheter is considered a promising device for quantifying …

Optical-based sensing approaches have long been an indispensable way to detect
molecules in biological tissues for various biomedical research and applications. The …

An unmet need exists in high-speed and highly-sensitive intraoperative assessment of
breast cancer margin during conservation surgical procedures. Here, we demonstrate a …

Lipid deposition can be assessed with combined intravascular photoacoustic/ultrasound
(IVPA/US) imaging. To date, the clinical translation of IVPA/US imaging has been stalled by …

The quantized vibration of chemical bonds provides a way of detecting specific molecules in
a complex tissue environment. Unlike pure optical methods, for which imaging depth is …

Intravascular photoacoustic tomography is an emerging technology for mapping lipid
deposition within an arterial wall for the investigation of the vulnerability of atherosclerotic …

Near-infrared photoacoustics receives increasing interest as an intravital modality to sense
key biomolecules. One of the most central types of biomolecules of interest are lipids as they …