Purpose: Diabetes is one of the important and growing diseases in the world. Among the
most common diabetic complications are renal adverse effects. The use of apigenin may …

Diabetic nephropathy (DN) is a serious complication of diabetes with a poorly defined
etiology and limited treatment options. Early intervention is key to preventing the progression …

Abstract Background. Ischaemia/reperfusion (I/R) is an important factor in delayed graft
function in renal transplantation and is a determinant of long-term graft outcome. This study …

Polycystic kidney disease is an inherited degenerative disease in which the uriniferous
tubules are replaced by expanding fluid-filled cysts that ultimately destroy organ function …

Abstract Aims Long noncoding RNAs (lncRNAs) are implicated in various biological
processes and human diseases. Diabetic nephropathy (DN) is the leading cause of end …

Abstract Peroxiredoxin 6 (PRDX6) is a member of the PRDX family of antioxidant enzymes
and correlated with inflammatory response. Therefore, we investigated the role of PRDX6 …

Prevention of progressive renal function loss and its complications remains the main
challenge in clinical nephrology. Although current therapeutic strategies aiming at reduction …

c-Jun N-terminal kinase (JNK) contributes to the pathogenesis of diabetic nephropathy (DN).
The JNK inhibitor SP600125 was reported to ameliorate DN. However, the mechanism …

Diabetic nephropathy (DN) is one of the most severe complications that can occur in patients
with diabetes, and without effective and timely therapeutic intervention, can gradually …

Background/Aims: The c-Jun amino-terminal kinase (JNK) signaling pathway is activated in
human kidney diseases and promotes renal injury in experimental glomerulonephritis. In …