Cutting-Edge Therapies for Lung Cancer

AS La'ah, SH Chiou - Cells, 2024 - mdpi.com
Lung cancer remains a formidable global health challenge that necessitates inventive
strategies to improve its therapeutic outcomes. The conventional treatments, including …

Gut microbial metabolites in lung cancer development and immunotherapy: Novel insights into gut-lung axis

X Li, S Shang, M Wu, Q Song, D Chen - Cancer Letters, 2024 - Elsevier
Metabolic derivatives of numerous microorganisms inhabiting the human gut can participate
in physiological activities and immune status of the lungs through the gut-lung axis. The …

[HTML][HTML] Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes

K Zhu, J Shi, R Yang, C Zhou, Z Liu - Neoplasia, 2023 - Elsevier
Objective This study aimed to investigate the causal relationship between mitochondrial
biological function and lung cancer, including its subtypes, via MR. Methods SNPs …

Differentially expressed genes involved in primary resistance to immunotherapy in patients with advanced-stage pulmonary cancer

LM Chinchilla-Tábora, JC Montero… - International Journal of …, 2024 - mdpi.com
In the last few years, nivolumab has become the standard of care for advanced-stage lung
cancer patients. Unfortunately, up to 60% of patients do not respond to this treatment. In our …

Identification of C-PLAN index as a novel prognostic predictor for advanced lung cancer patients receiving immune checkpoint inhibitors

J Wang, H Guo, J Yang, J Mao, Y Wang, X Yan… - Frontiers in …, 2024 - frontiersin.org
Objective Increasing studies have highlighted the potential utility of non-invasive prognostic
biomarkers in advanced lung cancer patients receiving immune checkpoint inhibitor (ICI) …

Early-Stage Non-Small Cell Lung Cancer: Prevalence of Actionable Alterations in a Monocentric Consecutive Cohort

R Bruno, AM Poma, M Panozzi, A Lenzini, G Elia… - Cancers, 2024 - mdpi.com
Simple Summary The therapeutic scenario of early-stage (ES) non-small cell lung cancer
(NSCLC) is rapidly evolving. Precision medicine, including both targeted therapy and …

Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer (NSCLC) Treatment: Quo Vadis?

AN Gargalionis, KA Papavassiliou… - International Journal of …, 2024 - mdpi.com
Lung cancer has been established as the second most common cancer worldwide (most
common cancer in men and second most common cancer in women) and as the leading …

Healthcare Resource Utilization and Associated Costs among Patients with Advanced Non-Small-Cell Lung Cancer Receiving Chemotherapy or Immunotherapy in …

J Ginés Rubió, O Delgado, A Callejo, M Domínguez… - Cancers, 2024 - mdpi.com
Simple Summary This observational, single-center, retrospective study aimed to describe
the real-world (RW) healthcare resource utilization (HCRU) among patients with advanced …

[HTML][HTML] The real-world insights on the use, safety, and outcome of immune-checkpoint inhibitors in underrepresented populations with lung cancer

X Hu, JH Lin, S Pan, YV Salei, SK Parsons - Cancer Treatment and …, 2024 - Elsevier
Background The data on immune checkpoint inhibitors (ICI) use in lung cancer individuals
generally underrepresented in clinical trials are limited. We aimed to examine the ICI …

[HTML][HTML] New developments and updates in non-small cell lung cancer and immunotherapy: adjuvant, neoadjuvant and advanced stages

A Olivares-Hernández, E del Barco-Morillo… - Annals of …, 2023 - ncbi.nlm.nih.gov
CI: 0.60–0.86). The other primary endpoint was OS and this was also met with data of 14.0
vs. 11.7 months (HR: 0.77; 95% CI: 0.65–0.92) respectively. Based on these data …