Background Functional constipation is a common functional bowel disorder in the
community, which has a varying prevalence across cross-sectional surveys. We did a …

Constipation is a common community health problem. There are many factors that are
widely thought to be associated with constipation but real-world evidence of these …

Emerging evidences suggest that gut microbiota dysbiosis plays a role in Parkinson's
disease (PD). However, the alterations in fecal microbiome in Chinese PD patients remains …

Background A subset of patients with constipation has reduced colonic bile acid
concentrations, which are associated with slow colonic transit. In a previous study …

Background Constipation and obesity have common risk factors. However, little is known
about the occurrence of constipation in individuals with severe obesity and the associated …

Methods An online questionnaire composed of items on the frequency, interval, form of
defecation, the management, and self-recognition of constipation (reference standard of …

Abstract Serotonin (5-HT) and the serotonin transporter (SERT) have earned a tremendous
amount of attention regarding the pathogenesis of irritable bowel syndrome (IBS) …

Background Irritable bowel syndrome (IBS) is a complex, heterogeneous disease which can
be challenging to diagnose. No study has identified and assessed the accuracy of all …

Background Different definitions of constipation have been used to estimate its prevalence
in the community but this creates difficulties when comparing results from various studies …

The objective was to determine the effects of prebiotics and synbiotics on adults with
functional constipation (FC). Medline, Embase and the Cochrane Library were searched for …