[HTML][HTML] ANRIL: A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease

Y Kong, CH Hsieh, LC Alonso - Frontiers in endocrinology, 2018 - frontiersin.org
The CDKN2A/B genomic locus is associated with risk of human cancers and metabolic
disease. Although the locus contains several important protein-coding genes, studies …

Epigenetic regulation in human melanoma: past and future

D Sarkar, EY Leung, BC Baguley, GJ Finlay… - Epigenetics, 2015 - Taylor & Francis
The development and progression of melanoma have been attributed to independent or
combined genetic and epigenetic events. There has been remarkable progress in …

LncRNAs as potential diagnostic and prognostic biomarkers in gastric cancer: a novel approach to personalized medicine

S Fattahi, M Kosari‐Monfared… - Journal of cellular …, 2020 - Wiley Online Library
Gastric cancer is the third leading cause of cancer death with 5‐year survival rate of about
30–35%. Since early detection is associated with decreased mortality, identification of novel …

Long noncoding RNAs in cancer: from function to translation

A Sahu, U Singhal, AM Chinnaiyan - Trends in cancer, 2015 - cell.com
While our understanding of the molecular mechanisms underlying cancer has significantly
improved, most of our knowledge focuses on protein-coding genes that make up a fraction of …

[HTML][HTML] Crosstalk between long noncoding RNAs and microRNAs in health and disease

AS Bayoumi, A Sayed, Z Broskova, JP Teoh… - International journal of …, 2016 - mdpi.com
Protein-coding genes account for only a small part of the human genome; in fact, the vast
majority of transcripts are comprised of non-coding RNAs (ncRNAs) including long ncRNAs …

[HTML][HTML] Epigenetic silencing of tumor suppressor genes: Paradigms, puzzles, and potential

A Kazanets, T Shorstova, K Hilmi, M Marques… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Cancer constitutes a set of diseases with heterogeneous molecular pathologies. However,
there are a number of universal aberrations common to all cancers, one of these being the …

[HTML][HTML] Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16

R Kong, E Zhang, D Yin, L You, T Xu, W Chen, R Xia… - Molecular cancer, 2015 - Springer
Background Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a
pivotal role in cancer biology. However, the overall biological role and clinical significance of …

TUG 1: a pivotal oncogenic long non‐coding RNA of human cancers

Z Li, J Shen, MTV Chan, WKK Wu - Cell proliferation, 2016 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are a group greater than 200 nucleotides in length. An
increasing number of studies has shown that lnc RNA s play important roles in diverse …

Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer

J Zhao, Y Liu, W Zhang, Z Zhou, J Wu, P Cui, Y Zhang… - Cell cycle, 2015 - Taylor & Francis
Gastric cancer remains a serious threat to public health with high incidence and mortality
worldwide. Accumulating evidence demonstrates that long non-coding RNAs (lncRNAs) …

Long noncoding RNAs: novel insights into gastric cancer

X Fang, H Pan, R Leng, D Ye - Cancer letters, 2015 - Elsevier
Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides. Recent
advances in the non-protein coding part of human genome analysis have discovered …