[HTML][HTML] Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression

F Nie, X Yu, M Huang, Y Wang, M Xie, H Ma, Z Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recently, long noncoding RNAs have been emerged as critical regulators of human disease
and prognostic markers in several cancers, including gastric cancer. In this study, we …

[HTML][HTML] Long noncoding RNA LINC00673 is activated by SP1 and exerts oncogenic properties by interacting with LSD1 and EZH2 in gastric cancer

M Huang, J Hou, Y Wang, M Xie, C Wei, F Nie, Z Wang… - Molecular Therapy, 2017 - cell.com
Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of
human diseases, including cancers. However, the biological function of these molecules …

From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer

MS Hussain, ASA Altamimi, M Afzal, I Kazmi… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

[HTML][HTML] LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose …

ZW Zou, C Ma, L Medoro, L Chen, B Wang, R Gupta… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long noncoding RNAs play a vital role in diverse biological processes such as embryonic
development, cell growth, and tumorigenesis. In this study, we report that LncRNA ANRIL …

[HTML][HTML] A pathophysiological view of the long non-coding RNA world

F Di Gesualdo, S Capaccioli, M Lulli - Oncotarget, 2014 - ncbi.nlm.nih.gov
Because cells are constantly exposed to micro-environmental changes, they require the
ability to adapt to maintain a dynamic equilibrium. Proteins are considered critical for the …

[HTML][HTML] Low expression of long noncoding RNA PANDAR predicts a poor prognosis of non-small cell lung cancer and affects cell apoptosis by regulating Bcl-2

L Han, EB Zhang, DD Yin, R Kong, TP Xu… - Cell death & …, 2015 - nature.com
Recently, a novel class of transcripts, long noncoding RNAs (lncRNAs), is involved in
diseases including cancer. Here, we investigated the the role of lncRNA PANDAR in the …

Interplay between long non-coding RNAs and epigenetic machinery: emerging targets in cancer?

DJ Hanly, M Esteller… - … Transactions of the …, 2018 - royalsocietypublishing.org
Of the diverse array of putative molecular and biological functions assigned to long non-
coding RNAs (lncRNAs), one attractive perspective in epigenetic research has been the …

Regulatory roles of long noncoding RNAs implicated in cancer hallmarks

J Wang, X Zhang, W Chen, X Hu, J Li… - International journal of …, 2020 - Wiley Online Library
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …

Long non-coding RNA signature in gastric cancer

S Ghafouri-Fard, M Taheri - Experimental and Molecular Pathology, 2020 - Elsevier
Gastric cancer as a common human malignancy has been associated with aberrant
expressions of several coding and non-coding genes. Long non-coding RNAs (lncRNAs) as …

[HTML][HTML] lncRNA ANRIL aggravates the chemoresistance of pancreatic cancer cells to gemcitabine by targeting inhibition of miR-181a and targeting HMGB1-induced …

L Wang, R Bi, L Li, K Zhou, H Yin - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Recent studies focus on long noncoding RNAs (lncRNA) as crucial regulators of cancer
biology that contribute to essential cancer cell functions such as cell proliferation, apoptosis …