[HTML][HTML] Cardiac reverse remodeling in ischemic heart disease with novel therapies for heart failure with reduced ejection fraction

SA Leancă, I Afrăsânie, D Crișu, IT Matei, ȘT Duca… - Life, 2023 - mdpi.com
Despite the improvements in the treatment of coronary artery disease (CAD) and acute
myocardial infarction (MI) over the past 20 years, ischemic heart disease (IHD) continues to …

[HTML][HTML] Omecamtiv Mecarbil in the treatment of heart failure: the past, the present, and the future

S Zhou, Y Liu, X Huang, C Wu… - Frontiers in …, 2024 - frontiersin.org
Heart failure, a prevailing global health issue, imposes a substantial burden on both
healthcare systems and patients worldwide. With an escalating prevalence of heart failure …

[HTML][HTML] Eligibility for omecamtiv mecarbil in a real-world heart failure population: Data from the Swedish Heart Failure Registry

F Lindberg, N Øigaard, M Metra, GMC Rosano… - Plos one, 2024 - journals.plos.org
Aims We assessed eligibility for omecamtiv mecarbil (OM) in a real-world cohort with heart
failure with reduced ejection fraction (HFrEF) according to the selection criteria of the …

Potential of phage display antibody technology for cardiovascular disease immunotherapy

SG Yeoh, JS Sum, JY Lai, WYH W Isa… - Journal of Cardiovascular …, 2022 - Springer
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. CVD
includes coronary artery diseases such as angina, myocardial infarction, and stroke.“Lipid …

Magnetic nanoparticles and their hybrid biomaterials for drug delivery and theranostic applications in cardiovascular diseases

Z Salmanpour, SS Abolmaali, G Farahavr… - Journal of Drug Delivery …, 2024 - Elsevier
Cardiovascular diseases stand as a leading cause of death worldwide, incurring substantial
medical costs and care. Despite significant advancements in diagnosing and treating these …

[HTML][HTML] Beyond Quadruple Therapy and Current Therapeutic Strategies in Heart Failure with Reduced Ejection Fraction: Medical Therapies with Potential to Become …

C Kourek, A Briasoulis, A Papamichail… - International Journal of …, 2024 - mdpi.com
Heart failure with reduced ejection fraction (HFrEF) is a complex clinical syndrome with
significant morbidity and mortality and seems to be responsible for approximately 50% of …

Distinct Mechanisms for Increased Cardiac Contraction Through Selective Alteration of Either Myosin or Troponin Activity

RR Singh, RE Slater, J Wang, C Wang, Q Guo… - Basic to Translational …, 2022 - jacc.org
Modulation of sarcomere contractility represents a new therapeutic opportunity for the
treatment of heart failure by directly targeting the thick and thin filament proteins of the …

伴有失代偿性心力衰竭慢性肾脏病的正性肌力药物的选择与应用

孙雪峰 - 中国血液净化, 2022 - cjbp.org.cn
正性肌力药物是治疗失代偿性心力衰竭的常用药物, 但慢性肾脏病患者如何选择与应用,
缺乏指导性意见. 本文在介绍不同种类正性肌力药物的药理作用基础上, 基于循证证据评价正性 …

Filling the Gaps in Guideline-Directed Care.

C Betz - American Journal of Managed Care, 2021 - search.ebscohost.com
As American clinicians have tried to reduce heart failure rehospitalizations and improve care
for patients with heart failure with reduced ejection fraction (HFrEF), the population of …

[HTML][HTML] Reverse Remodeling of Methamphetamine-Associated Cardiomyopathy: An Update on Mechanisms for Recovery

JR Richards, AR Danielson, RP Stuart… - Medical Research …, 2024 - esmed.org
Methamphetamine (MA) use continues to rise worldwide. The adverse effects of MA on the
cardiovascular system include cardiomyopathy, dysrhythmias, coronary arterial vasospasm …