Molecular recognition in chemical and biological systems

E Persch, O Dumele, F Diederich - … Chemie International Edition, 2015 - Wiley Online Library
Abstract Structure‐based ligand design in medicinal chemistry and crop protection relies on
the identification and quantification of weak noncovalent interactions and understanding the …

Chemistry of the retinoid (visual) cycle

PD Kiser, M Golczak, K Palczewski - Chemical reviews, 2014 - ACS Publications
As succinctly summarized by Wolf, 1 lack of vitamin A (all-trans-retinol) was recognized by
ancient Egyptians as causing a visual deficiency involving the retina and cornea that could …

[HTML][HTML] Molecular and biotechnological aspects of secondary metabolites in actinobacteria

R Salwan, V Sharma - Microbiological research, 2020 - Elsevier
The ability to produce plethora of secondary metabolites and enzymes for pharmaceutical,
agricultural and biotechnological applications make actinobacteria one of the most explored …

Carotenoids, versatile components of oxygenic photosynthesis

I Domonkos, M Kis, Z Gombos, B Ughy - Progress in lipid research, 2013 - Elsevier
Carotenoids (CARs) are a group of pigments that perform several important physiological
functions in all kingdoms of living organisms. CARs serve as protective agents, which are …

Methylerythritol phosphate pathway of isoprenoid biosynthesis

L Zhao, W Chang, Y Xiao, H Liu… - Annual review of …, 2013 - annualreviews.org
Isoprenoids are a class of natural products with more than 55,000 members. All isoprenoids
are constructed from two precursors, isopentenyl diphosphate and its isomer dimethylallyl …

ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan

I Gerin, B Ury, I Breloy, C Bouchet-Seraphin… - Nature …, 2016 - nature.com
Mutations in genes required for the glycosylation of α-dystroglycan lead to muscle and brain
diseases known as dystroglycanopathies. However, the precise structure and biogenesis of …

Current development in isoprenoid precursor biosynthesis and regulation

W Chang, H Song, H Liu, P Liu - Current opinion in chemical biology, 2013 - Elsevier
Highlights•Isoprenoids are widely utilized in biomedical and commercial
applications.•Recent progress in understanding the biosynthesis of DMAPP and IPP is …

Plant anthraquinones: classification, distribution, biosynthesis, and regulation

P Wang, J Wei, X Hua, G Dong… - Journal of Cellular …, 2023 - Wiley Online Library
Anthraquinones are polycyclic compounds with an unsaturated diketone structure (quinoid
moiety). As important secondary metabolites of plants, anthraquinones play an important …

Targeting lipid biosynthesis and salvage in apicomplexan parasites for improved chemotherapies

I Coppens - Nature Reviews Microbiology, 2013 - nature.com
Apicomplexa are some of the most widespread and poorly controlled pathogens in the
world. The metabolism of lipids in these parasites, which include Plasmodium spp …

Over‐expression of DXS gene enhances terpenoidal secondary metabolite accumulation in rose‐scented geranium and Withania somnifera: active involvement of …

JS Jadaun, NS Sangwan, LK Narnoliya… - Physiologia …, 2017 - Wiley Online Library
Rose‐scented geranium (Pelargonium spp.) is one of the most important aromatic plants
and is well known for its diverse perfumery uses. Its economic importance is due to presence …