T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitory receptor expressed
on several types of lymphocytes. Efficacy of antibody blockade of TIGIT in cancer …

Despite the impressive results of autologous CAR-T cell therapy in refractory B
lymphoproliferative diseases, CAR-NK immunotherapy emerges as a safer, faster, and cost …

Tumor mutational burden (TMB) has been reported to determine the response to
immunotherapy, thus affecting the patient's prognosis in many cancers. However, it is …

Simple Summary Recent years marked the discovery and increased understanding of the
role immune checkpoints play in immunity against cancer. This has revolutionized cancer …

Immune checkpoints (ICs), also referred to as co-inhibitory receptors (IRs), are essential for
regulating immune cell function to maintain tolerance and prevent autoimmunity. IRs, such …

The continuous, in-depth exploration of the occurrence and development of cancer has
shown that immune cell dysfunction is closely associated with tumor progression and poor …

Pancreatic cancer (PC) is the most lethal malignancy worldwide due to its delayed diagnosis
and limited treatment options. Despite great progress in clinical trials of immunotherapies for …

This study aimed to characterize different natural killer (NK) cell phenotypes on bone
marrow and peripheral blood cells from acute myeloid leukemia (AML) patients and healthy …

Immunotherapy has revolutionized cancer treatment with the advent of advanced cell
engineering techniques aimed at targeted therapy with reduced systemic toxicity. However …

Background: Prostate cancer (PCa) and a novel ferroptosis-related gene prognostic index
(FGPI) was constructed to predict biochemical recurrence (BCR) and radiation resistance for …