The electronic properties and relatively small size of fluorine endow it with considerable
versatility as a bioisostere and it has found application as a substitute for lone pairs of …

Over the past decade, the most significant, conceptual advances in the field of fluorination
were enabled most prominently by organo‐and transition‐metal catalysis. The most …

The design of bioisosteres represents a creative and productive approach to improve a
molecule, including by enhancing potency, addressing pharmacokinetic challenges …

The enzymatic generation of carbon–halogen bonds is a powerful strategy used by both
nature and synthetic chemists to tune the bioactivity, bioavailability and reactivity of …

One goal of this review is to bring out that the chemical enterprise needs to work to reduce
society's uncertainties with respect to the safety of persistent or pseudopersistent …

While F is an essential constituent of some rock-forming minerals such as fluorite and
apatite, its major occurrence in the lithosphere is within hydroxysilicate minerals where F …

Die wichtigsten konzeptionellen Fortschritt auf dem Gebiet der Fluorierungen der letzten
zehn Jahre wurden durch die Organo‐und Übergangsmetallkatalyse ermöglicht. Die …

The past 30 years have witnessed a period of significant expansion in the use of
halogenated compounds in the field of agrochemical research and development. The …

An efficient palladium‐catalyzed Heck‐type reaction of fluoroalkyl halides, including
perfluoroalkyl bromides, trifluoromethyl iodides, and difluoroalkyl bromides, has been …

Fluorinated pesticides acquired a significant market share in the agrochemical sector due to
the surge of new fluoroorganic ingredients approved in the last two decades. This growing …