[HTML][HTML] Nanopore-based technologies beyond DNA sequencing

YL Ying, ZL Hu, S Zhang, Y Qing, A Fragasso… - Nature …, 2022 - nature.com
Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Disulfide-mediated reversible polymerization toward intrinsically dynamic smart materials

Q Zhang, DH Qu, BL Feringa… - Journal of the American …, 2022 - ACS Publications
The development of a dynamic chemistry toolbox to endow materials dynamic behavior has
been key to the rational design of future smart materials. The rise of supramolecular and …

Electrochemical sensing at a confined space

SM Lu, YY Peng, YL Ying, YT Long - Analytical chemistry, 2020 - ACS Publications
Single entity sensing is recently an area of tremendous interest in analytical chemistry, such
that it is possible to analyze single cells, single particles, and even single molecules. Among …

Thiol-mediated uptake

Q Laurent, R Martinent, B Lim, AT Pham, T Kato… - Jacs Au, 2021 - ACS Publications
This Perspective focuses on thiol-mediated uptake, that is, the entry of substrates into cells
enabled by oligochalcogenides or mimics, often disulfides, and inhibited by thiol-reactive …

[HTML][HTML] Dual closed-loop chemical recycling of synthetic polymers by intrinsically reconfigurable poly (disulfides)

Q Zhang, Y Deng, CY Shi, BL Feringa, H Tian, DH Qu - Matter, 2021 - cell.com
The excessive use of plastics has led to severe global problems involving environmental,
energy, and health issues and demands for sustainable and recyclable alternatives. Toward …

Optical sequencing of single synthetic polymers

R Ye, X Sun, X Mao, FS Alfonso, S Baral, C Liu… - Nature Chemistry, 2024 - nature.com
Microscopic sequences of synthetic polymers play crucial roles in the polymer properties,
but are generally unknown and inaccessible to traditional measurements. Here we report …

Room-Temperature Grafting from Synthesis of Protein–Polydisulfide Conjugates via Aggregation-Induced Polymerization

J Lu, Z Xu, H Fu, Y Lin, H Wang… - Journal of the American …, 2022 - ACS Publications
The reversible modification of proteins with lipoic acid (LPA)-derived polydisulfides (PDS) is
an important approach toward the transient regulation and on-demand recovery of protein …

Controllable disulfide exchange polymerization of polyguanidine for effective biomedical applications by thiol‐mediated uptake

Y Zhu, M Lin, W Hu, J Wang, ZG Zhang… - Angewandte …, 2022 - Wiley Online Library
New preparation methods of vectors are the key to developing the next generation of
biomacromolecule delivery systems. In this study, a controllable disulfide exchange …

Unraveling the pivotal role of atropisomerism for cellular internalization

C Donohoe, FA Schaberle… - Journal of the …, 2022 - ACS Publications
The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular
targets is a major obstacle for the development of new medicines. We report how rotation …