COPD in China: the burden and importance of proper management

X Fang, X Wang, C Bai - Chest, 2011 - Elsevier
Although, to our knowledge, there has been no exhaustive or credible review of the
evidence of the disease burden of COPD in China, COPD has become an increasing public …

Updates on the COPD gene list

Y Bossé - International journal of chronic obstructive pulmonary …, 2012 - Taylor & Francis
A genetic contribution to develop chronic obstructive pulmonary disease (COPD) is well
established. However, the specific genes responsible for enhanced risk or host differences …

Polymorphism of SERPINE2 gene is associated with pulmonary emphysema in consecutive autopsy cases

K Fujimoto, S Ikeda, T Arai, N Tanaka, T Kumasaka… - BMC Medical …, 2010 - Springer
Abstract Background The SERPINA1, SERPINA3, and SERPINE2 genes, which encode
antiproteases, have been proposed to be susceptible genes for of chronic obstructive …

Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes

JQ Zhang, JQ Zhang, H Liu, ZH Zhao… - … journal of chronic …, 2015 - Taylor & Francis
Background The role of the antioxidant N-acetylcysteine (NAC) in the treatment of chronic
obstructive pulmonary disease (COPD) has not been clarified as yet. In early studies, we …

SERPINE2 haplotype as a risk factor for panlobular type of emphysema

MK Kukkonen, E Tiili, S Hämäläinen, T Vehmas… - BMC medical …, 2011 - Springer
Background SERPINE2 (serpin peptidase inhibitor, clade E, member 2) has previously been
identified as a positional candidate gene for chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] Genome-wide association study of copy number variations associated with pulmonary function measures in Korea Associated Resource (KARE) cohorts

BY Lee, S Cho, DH Shin, H Kim - Genomics, 2011 - Elsevier
Copy number variation (CNV) is an attractive emerging approach to study the association
with various diseases. We performed a CNV-based genome-wide association study of …

Association of SERPINE2 gene with the risk of chronic obstructive pulmonary disease and spirometric phenotypes in northern Han Chinese population

L An, T Yang, Y Zhang, Y Lin, H Zhang, X Jiao… - Molecular biology …, 2012 - Springer
Chronic obstructive pulmonary disease (COPD) is a complex human disease influenced by
multiple genes and environmental factors. The SERPINE2 gene has recently been …

Protease nexin-1: a serpin involved in pathophysiology

V Arocas, MC Bouton - The Serpin Family: Proteins with Multiple Functions …, 2015 - Springer
Abstract Protease nexin-1 (PN-1), also known as SERPINE2, is the phylogenetically closest
relative of plasminogen activator type 1 (PAI-1). Unlike PAI-1, antithrombin (AT), protein C …

The Relationship between GSTP1 I105V Polymorphism and COPD: A Reappraisal

L Zhong, YP Zhang, WP Fu, LM Dai, C Sun… - American journal of …, 2010 - atsjournals.org
In a recent issue of the Journal, Smolonska and colleagues (1) performed a meta-analysis
on the relation between the glutathione S-transferase P1 (GSTP1) I105V polymorphism …

[PDF][PDF] Association between the rs3795879 G/A polymorphism of the SERPINE2 gene and chronic obstructive pulmonary disease: a meta-analysis

DB Tian, SX Cai, GC Pan, YF Zhang, JH Xiao - Genet Mol Res, 2015 - funpecrp.com.br
The present study aimed to investigate the effects of the rs3795879 polymorphism of the
SERPINE2 gene on the development of chronic obstructive pulmonary disease (COPD) …