Secondary analysis of electronic health records for clinical research faces significant
challenges due to known data quality issues in health data observationally collected for …

Background Many research initiatives aim at using data from electronic health records
(EHRs) in observational studies. Participating sites of the German Medical Informatics …

OBJECTIVES The goal of this study was to determine the incidence, prognostic
performance, and generalizability of the Pediatric Organ Dysfunction Information Update …

Background and objective In recent years, several data quality conceptual frameworks have
been proposed across the Data Quality and Information Quality domains towards …

Federated networks of observational health databases have the potential to be a rich
resource to inform clinical practice and regulatory decision making. However, the lack of …

Genomic data are growing at unprecedented pace, along with new protocols, update
polices, formats and guidelines, terminologies and ontologies, which are made available …

Introduction Despite improvements in prevention of mother‐to‐child transmission (PMTCT)
of HIV outcomes, there remain unacceptably high numbers of mother‐to‐child transmissions …

Heterogeneity is a pervasive feature of critical illness syndromes. Patients in the intensive
care unit (ICU) are injured or develop critical illness for a plethora of reasons. On any given …

Aim The increasing availability of Big Biomedical Data is leading to large research data
samples collected over long periods of time. We propose the analysis of the kinematics of …

Objective Due to a complex set of processes involved with the recording of health
information in the Electronic Health Records (EHRs), the truthfulness of EHR diagnosis …