The first, holistic immunological model of COVID‐19: implications for prevention, diagnosis, and public health measures

PM Matricardi, RW Dal Negro… - Pediatric Allergy and …, 2020 - Wiley Online Library
The natural history of COVID‐19 caused by SARS‐CoV‐2 is extremely variable, ranging
from asymptomatic or mild infection, mainly in children, to multi‐organ failure, eventually …

Limited innovations after more than 65 years of immunoglobulin replacement therapy: potential of IgA-and IgM-enriched formulations to prevent bacterial respiratory …

JD Langereis, M Van der Flier… - Frontiers in Immunology, 2018 - frontiersin.org
Patients with primary immunoglobulin deficiency have lower immunoglobulin levels or
decreased immunoglobulin function, which makes these patients more susceptible to …

Clinical and immunological phenotypes of selective IgM deficiency in children: Results from a multicenter study

R Castagnoli, I Taietti, M Votto, M Naso… - Pediatric Allergy and …, 2023 - Wiley Online Library
Background A few studies assessed the clinical and immunological features of selective IgM
deficiency (SIgMD), especially in the pediatric age. We aimed to characterize the clinical and …

Selective IgM deficiency: evidence, controversies, and gaps

I Taietti, M Votto, M De Filippo, M Naso, L Montagna… - Diagnostics, 2023 - mdpi.com
Selective Immunoglobulin M deficiency (SIgMD) has been recently included in the inborn
errors of immunity (IEI) classification by the International Union of Immunological Societies …

Immunoglobulin abnormalities are frequent in patients with lupus nephritis

MJ Cuadrado, I Calatayud, M Urquizu-Padilla… - BMC rheumatology, 2019 - Springer
Background Hypogammaglobulinemia is a complication of B-cell targeting therapies
(BCTT), used in vasculitis, rheumatoid arthritis and systemic lupus erythematosus (SLE) …

Defining primary selective IgM deficiency

S Gupta, A Gupta - Journal of clinical immunology, 2019 - Springer
To The Editor: Selective IgM deficiency (also previously known as type V
dysgammaglobulinemia) was described more than 50 years ago in two children with …

Challenges in investigating patients with isolated decreased serum IgM: The SIMcal study

LMA Janssen, RWNM van Hout… - Scandinavian …, 2019 - Wiley Online Library
The clinical consequences of isolated decreased serum immunoglobulin (Ig) M are not
sufficiently known. Therefore, it is difficult to determine the clinical policy following such a …

The epidemiology and clinical features of selective immunoglobulin M deficiency: a single‐center study in China

J Ni, J Zhang, Q Chen, Y Chen… - Journal of clinical …, 2020 - Wiley Online Library
Background Selective immunoglobulin M deficiency (SIgMD) is a rare primary
immunodeficiency that is frequently reported in Western countries. However, large …

[HTML][HTML] Conceptos generales de las inmunodeficiencias humorales

MG Velásquez-Ortiz, PM O'Farrill-Romanillos… - Revista alergia …, 2020 - scielo.org.mx
Las inmunodeficiencias humorales (IDH) comprenden un grupo de enfermedades
caracterizadas por la imposibilidad de desarrollar una respuesta inmune efectiva mediada …

Acute-onset autoimmune hepatitis in a patient with selective immunoglobulin M deficiency

A Sano, J Inoue, E Kakazu, M Ninomiya, T Iwata… - Internal …, 2019 - jstage.jst.go.jp
Selective immunoglobulin M deficiency (SIGMD) is an uncommon primary
immunodeficiency disorder. We herein report an SIGMD patient with autoimmune hepatitis …