[HTML][HTML] The role of the mTOR pathway in diabetic retinopathy

F Casciano, E Zauli, E Rimondi, M Mura… - Frontiers in …, 2022 - frontiersin.org
The retina is the part of the eye that translates light signal into an electric current so that it
can be sent to the brain as visual information. To do that, the retina requires fine-tuned …

Decellularized extracellular matrix: the role of this complex biomaterial in regeneration

AGP de Paula, JD de Lima, TSB Bastos… - ACS …, 2023 - ACS Publications
Organ transplantation is understood as a technique where an organ from a donor patient is
transferred to a recipient patient. This practice gained strength in the 20th century and …

Optic neuropathies: Current and future strategies for optic nerve protection and repair

NR Miller, RK Tsai - International Journal of Molecular Sciences, 2023 - mdpi.com
Processes that damage the optic nerve, including elevated intraocular pressure, trauma,
ischemia, and compression, often cause visual loss for which there is no current treatment. It …

Disentangling multiple sclerosis phenotypes through Mendelian disorders: A network approach

G Bellucci, MC Buscarinu, R Reniè… - Multiple Sclerosis …, 2024 - journals.sagepub.com
Background: The increasing knowledge about multiple sclerosis (MS) pathophysiology has
reinforced the need for an improved description of disease phenotypes, connected to …

[HTML][HTML] Erythropoietin Protects against Retinal Damage in A Rat Model of Optic Neuropathy via Glial Suppression

A Eghbali, Y Anvarinia, MS Sanjari, F Pakdel… - Cell Journal …, 2023 - ncbi.nlm.nih.gov
Objective: Traumatic optic neuropathy (TON) causes partial or complete blindness because
death of irreplaceable retinal ganglion cells (RGCs). Neuroprotective functions of …

Vorgehen bei frontobasalen Frakturen

F Sommer, M Brand, MO Scheithauer, TK Hoffmann… - HNO, 2023 - Springer
Zusammenfassung Schädel-Hirn-Traumata können zu frontobasalen Frakturen (FBF)
führen. Die Ziele der Therapie von FBF liegen in der Beseitigung einer primären Morbidität …

Anteriore ischämische Optikusneuropathie (AION)

C van Oterendorp, S Bemme - Die Augenheilkunde: Das Referenzwerk, 2023 - Springer
Die akute Ischämie des Sehnervs ist einer der Hauptgründe für eine plötzliche schmerzlose
Erblindung. Man unterscheidet die anteriore und die sehr seltene posteriore ischämische …

Nichtarteriitische anteriore ischämische Optikusneuropathie (nAION)

TR Beyer, C van Oterendorp - Die Ophthalmologie, 2023 - Springer
Die nichtarteriitische anteriore ischämische Optikusneuropathie (nAION) ist die
zweithäufigste Erkrankung, die zur Degeneration des Sehnervs führt. Die Pathogenese ist …

Commentary: Erythropoietin as a treatment option for indirect optic neuropathy: A pilot study

JL Goyal, N Holmes - Indian Journal of Ophthalmology, 2023 - journals.lww.com
In this pilot study, the advantages of adopting intravenous erythropoietin (EPO) as an option
for the treatment of indirect optic neuropathy, especially in cases where steroids are contra …

Structural Optimization of Antioxidant Copolymers for Drug Delivery Applications

CR DeJulius - 2023 - ir.vanderbilt.edu
Oxidative stress, the pathological elevation of reactive oxygen species (ROS), participates in
the propagation of many diseases, including osteoarthritis and optic neuropathies. Polymers …