Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …

Future RCTs should compare a 3–5 day nebulization of amikacin or colistimethate sodium
(CMS) to a 7-day intravenous administration of a new cephalosporine/ß-lactamase inhibitor …

Acoustofluidics has promised to enable lab-on-a-chip and point-of-care devices in ways
difficult to achieve using other methods. Piezoelectric ultrasonic transducers—as small as …

The use of nebulized antibiotics for treating ventilatorassociated pneumonia (VAP) caused
by multidrugresistant (MDR) Gram-negative bacteria (GNB) increases worldwide. There is a …

Background: Rising antimicrobial resistance has led to a revived interest in inhaled colistin
treatment in the critically ill patient with ventilator-associated respiratory infection (VARI) …

In this work, 13 jet nebulizers, some of which in different configurations, were investigated in
order to identify the biopharmaceutical constraints related to the quality attributes of the …

(1) Background: Colistin-only susceptible (COS) Acinetobacter baumannii (AB) ventilator-
associated pneumonia (VAP) represents a clinical challenge in the Intensive Care Unit (ICU) …

Background Nebulizers are medical devices that deliver aerosolized medication directly to
lungs to treat a variety of respiratory diseases. However, breathing patterns, respiration …

Background Nebulizers are commonly used to treat respiratory diseases, which are a major
cause of morbidity and mortality. While inhalation therapy with antibodies has been …

Global emergence of multidrug-resistant and extensive drug-resistant gram-negative
bacteria has increased the risk of treatment failure, especially for healthcare-or ventilator …