Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease
M Cazzola, F Cavalli, OS Usmani… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …
However, none of the available devices fully conforms to the requirements for delivering …
Nebulized antibiotics for ventilator-associated pneumonia: methodological framework for future multicenter randomized controlled trials
A Monsel, A Torres, Y Zhu, J Pugin… - Current opinion in …, 2021 - journals.lww.com
Future RCTs should compare a 3–5 day nebulization of amikacin or colistimethate sodium
(CMS) to a 7-day intravenous administration of a new cephalosporine/ß-lactamase inhibitor …
(CMS) to a 7-day intravenous administration of a new cephalosporine/ß-lactamase inhibitor …
Practical microcircuits for handheld acoustofluidics
A Huang, W Connacher, M Stambaugh, N Zhang… - Lab on a Chip, 2021 - pubs.rsc.org
Acoustofluidics has promised to enable lab-on-a-chip and point-of-care devices in ways
difficult to achieve using other methods. Piezoelectric ultrasonic transducers—as small as …
difficult to achieve using other methods. Piezoelectric ultrasonic transducers—as small as …
Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin
JJ Rouby, C Sole-Lleonart, J Rello - Intensive care medicine, 2020 - Springer
The use of nebulized antibiotics for treating ventilatorassociated pneumonia (VAP) caused
by multidrugresistant (MDR) Gram-negative bacteria (GNB) increases worldwide. There is a …
by multidrugresistant (MDR) Gram-negative bacteria (GNB) increases worldwide. There is a …
Pharmacokinetic characteristics of nebulized colistimethate sodium using two different types of nebulizers in critically ill patients with ventilator-associated respiratory …
Background: Rising antimicrobial resistance has led to a revived interest in inhaled colistin
treatment in the critically ill patient with ventilator-associated respiratory infection (VARI) …
treatment in the critically ill patient with ventilator-associated respiratory infection (VARI) …
Aerosolization performance of jet nebulizers and biopharmaceutical aspects
G Adorni, G Seifert, F Buttini, G Colombo… - Pharmaceutics, 2019 - mdpi.com
In this work, 13 jet nebulizers, some of which in different configurations, were investigated in
order to identify the biopharmaceutical constraints related to the quality attributes of the …
order to identify the biopharmaceutical constraints related to the quality attributes of the …
Use of High-Dose Nebulized Colistimethate in Patients with Colistin-Only Susceptible Acinetobacter baumannii VAP: Clinical, Pharmacokinetic and Microbiome …
(1) Background: Colistin-only susceptible (COS) Acinetobacter baumannii (AB) ventilator-
associated pneumonia (VAP) represents a clinical challenge in the Intensive Care Unit (ICU) …
associated pneumonia (VAP) represents a clinical challenge in the Intensive Care Unit (ICU) …
In vitro delivery efficiencies of nebulizers for different breathing patterns
HM Park, KH Chang, SH Moon, BJ Park… - Biomedical engineering …, 2021 - Springer
Background Nebulizers are medical devices that deliver aerosolized medication directly to
lungs to treat a variety of respiratory diseases. However, breathing patterns, respiration …
lungs to treat a variety of respiratory diseases. However, breathing patterns, respiration …
Evaluation of antibody drug delivery efficiency via nebulizer in various airway models and breathing patterns
SW Hong, KH Chang, CJ Woo, HC Kim… - BMC Pharmacology and …, 2023 - Springer
Background Nebulizers are commonly used to treat respiratory diseases, which are a major
cause of morbidity and mortality. While inhalation therapy with antibodies has been …
cause of morbidity and mortality. While inhalation therapy with antibodies has been …
Nebulized antibiotics for healthcare-and ventilator-associated pneumonia
M Boisson, A Bouglé, C Sole-Lleonart… - … in Respiratory and …, 2022 - thieme-connect.com
Global emergence of multidrug-resistant and extensive drug-resistant gram-negative
bacteria has increased the risk of treatment failure, especially for healthcare-or ventilator …
bacteria has increased the risk of treatment failure, especially for healthcare-or ventilator …