Thoracic VGluT2+ Spinal interneurons regulate structural and functional plasticity of sympathetic networks after high-level spinal cord injury

BT Noble, FH Brennan, Y Wang, Z Guan… - Journal of …, 2022 - Soc Neuroscience
Traumatic spinal cord injury (SCI) above the major spinal sympathetic outflow (T6 level)
disinhibits sympathetic neurons from supraspinal control, causing systems-wide …

Cardiometabolic risk factors in experimental spinal cord injury

J Inskip, W Plunet, L Ramer, JB Ramsey… - Journal of …, 2010 - liebertpub.com
Cardiometabolic risk factors are sorely underreported after spinal cord injury (SCI), despite
the high prevalence of metabolic disorders and cardiovascular mortality in this population …

[HTML][HTML] Chronic spinal cord injury attenuates influenza virus-specific antiviral immunity

V Bracchi-Ricard, J Zha, A Smith… - Journal of …, 2016 - Springer
Background Individuals suffering from spinal cord injury (SCI) are at higher risk for
respiratory-related viral infections such as influenza. In a previous study (Zha et al., J …

Depression-like behavior corresponds with cardiac changes in a rodent model of spinal cord injury

K Brakel, AR Aceves, M Aceves, A Hierholzer… - Experimental …, 2019 - Elsevier
In previous studies we have shown that approximately 1/3 of male Sprague Dawley rats
develop symptoms of depression following a spinal cord injury (SCI). Using established …

Effects of acute sacral neuromodulation on bladder reflex in complete spinal cord injury rats

P Shi, X Zhao, J Wang, N Lan - Neuromodulation: Technology at the Neural …, 2013 - Elsevier
Background Neurogenic bladder associated with spinal cord injury (SCI) often results in
serious disruption of lower urinary tract function. Compared to conventional therapies, sacral …

Characterization of supraspinal vasomotor pathways and autonomic dysreflexia after spinal cord injury in F344 rats

S Hou, P Lu, A Blesch - Autonomic neuroscience, 2013 - Elsevier
Cardiovascular dysfunction usually occurs after high thoracic and cervical spinal cord injury
(SCI). The disruption of supraspinal vasomotor pathways (SVPs) results in the loss of …

[HTML][HTML] Cardiovascular and cerebrovascular responses to urodynamics testing after spinal cord injury: The influence of autonomic injury

IS Sahota, VEM Lucci, MS McGrath… - Frontiers in …, 2022 - frontiersin.org
Autonomic dysfunction is a prominent concern following spinal cord injury (SCI). In
particular, autonomic dysreflexia (AD; paroxysmal hypertension and concurrent bradycardia …

Restoring neuro-immune circuitry after brain and spinal cord injuries

M Ueno - International Immunology, 2021 - academic.oup.com
Neuro-immune interactions are essential for our body's defense and homeostasis.
Anatomical and physiological analyses have shown that the nervous system comprises …

Combination therapies

M Oudega, EJ Bradbury, MS Ramer - Handbook of clinical neurology, 2012 - Elsevier
Spinal cord injury (SCI) has multiple consequences, ranging from molecular imbalances to
glial scar formation to functional impairments. It is logical to think that a combination of single …

Neuroprotection, plasticity manipulation, and regenerative strategies to improve cardiovascular function following spinal cord injury

JW Squair, CR West, AV Krassioukov - Journal of Neurotrauma, 2015 - liebertpub.com
Damage to the central nervous system, as in the case of spinal cord injury (SCI), results in
disrupted supraspinal sympathetic influence and subsequent cardiovascular control …