Testis development

JA Mäkelä, JJ Koskenniemi, HE Virtanen… - Endocrine …, 2019 - academic.oup.com
Production of sperm and androgens is the main function of the testis. This depends on
normal development of both testicular somatic cells and germ cells. A genetic program …

Spatiotemporal trends in human semen quality

J Auger, F Eustache, C Chevrier, B Jégou - Nature Reviews Urology, 2022 - nature.com
Over the past four decades, studies of various designs have reported spatial and temporal
trends in human semen quality. Several standardized-methodology studies in …

Semen quality in the 21st century

HE Virtanen, N Jørgensen, J Toppari - Nature Reviews Urology, 2017 - nature.com
Although semen quality is an important determinant of fertility, defining clear thresholds for
normal ranges has proven difficult. According to'time to pregnancy'studies, fecundity starts to …

Trend of change of sperm count and concentration over the last two decades: A systematic review and meta‐regression analysis

S Cipriani, E Ricci, F Chiaffarino, G Esposito… - …, 2023 - Wiley Online Library
Background Since the 1970s, several studies found that sperm concentration (SC) and total
sperm count (TSC) constantly worsened over time, mainly in high‐income countries …

Semen quality of young men in Switzerland: a nationwide cross‐sectional population‐based study

R Rahban, L Priskorn, A Senn, E Stettler, F Galli… - …, 2019 - Wiley Online Library
Background Sperm counts have been steadily decreasing over the past five decades with
regional differences in the Western world. The reasons behind these trends are complex, but …

Regional difference in semen quality of young men: a review on the implication of environmental and lifestyle factors during fetal life and adulthood

R Rahban, S Nef - Basic and clinical andrology, 2020 - Springer
The prevalence of low semen quality and the incidence of testicular cancer have been
steadily increasing over the past decades in different parts of the World. Although these …

Global trends in semen quality of young men: a systematic review and regression analysis

X Luo, C Yin, Y Shi, C Du, X Pan - Journal of assisted reproduction and …, 2023 - Springer
Purpose Many studies have reported declines in semen quality mainly focused on total
sperm counts (TSC) and sperm concentration (SC), ignoring the importance of progressive …

An age-based sperm nomogram: the McGill reference guide

M Salmon-Divon, G Shrem, J Balayla… - Human …, 2020 - academic.oup.com
STUDY QUESTION How does age affect various semen parameters? SUMMARY ANSWER
For most semen parameters, the nomogram of the entire population was biphasic, peaking …

Sperm mitochondrial function is affected by stallion age and predicts post-thaw motility

CR Darr, LE Moraes, TN Scanlan… - Journal of Equine …, 2017 - Elsevier
Sperm motility and quality decline with stallion age and sperm preservation, but the
mechanisms of functional deficit have not been explained. We tested the hypothesis that …

Semen quality in patients with pituitary disease and adult-onset hypogonadotropic hypogonadism

M Andreassen, A Juul… - Endocrine …, 2018 - ec.bioscientifica.com
Objective Gonadotropins (luteinizing hormone (LH) and follicle-stimulating hormone (FSH))
are released from the pituitary gland and stimulate Leydig cells to produce testosterone and …