[HTML][HTML] Use of biomaterials for sustained delivery of anti-VEGF to treat retinal diseases

I Seah, X Zhao, Q Lin, Z Liu, SZZ Su, YS Yuen… - Eye, 2020 - nature.com
Anti-vascular endothelial growth factors (anti-VEGF) have become the most common
treatment modality for many retinal diseases. These include neovascular age-related …

[HTML][HTML] Micropulse laser treatment of retinal diseases

M Gawęcki - Journal of Clinical Medicine, 2019 - mdpi.com
Subthreshold micropulse laser treatment has been intensively used for selected retinal
diseases in the last decade; however, the exact mechanism of the action of lasers in the …

The effect of delay in care among patients requiring intravitreal injections

W Song, RP Singh, AV Rachitskaya - Ophthalmology Retina, 2021 - Elsevier
Purpose To examine the effect of delay in care on visual acuity (VA) in patients requiring
intravitreal injections (IVIs). Design Retrospective cohort study. Participants Patients 18 …

[HTML][HTML] BALATON and COMINO: phase III randomized clinical trials of Faricimab for retinal vein occlusion: study design and rationale

LO Hattenbach, F Abreu, P Arrisi, K Basu… - Ophthalmology …, 2023 - Elsevier
Purpose Dual inhibition of angiopoietin-2 and VEGF-A with faricimab (Vabysmo) offers
excellent visual acuity gains with strong durability in patients with diabetic macular edema …

Real-world data: ranibizumab treatment for retinal vein occlusion in the OCEAN study

J Callizo, F Ziemssen, T Bertelmann… - Clinical …, 2019 - Taylor & Francis
Purpose The non-interventional OCEAN study (NCT02194803) evaluated frequency and
monitoring of ranibizumab injections for retinal vein occlusion (RVO) in routine practice in …

The correlation between cytokine levels in the aqueous humor and the prognostic value of anti-vascular endothelial growth factor therapy for treating macular edema …

H Yong, H Qi, H Yan, Q Wu, L Zuo - Graefe's Archive for Clinical and …, 2021 - Springer
Purpose To determine the correlation between aqueous humor cytokine levels and the
prognostic value of anti-vascular endothelial growth factor (VEGF) therapy for treating …

[HTML][HTML] Contribution of interleukin-17a to retinal degenerative diseases

H Zhong, X Sun - Frontiers in Immunology, 2022 - frontiersin.org
Retinal degenerative diseases are a leading cause of vision loss and blindness throughout
the world, characterized by chronic and progressive loss of neurons and/or myelin. One of …

[HTML][HTML] Anti-IL17a halts the onset of diabetic retinopathy in type I and II diabetic mice

AY Zhou, BE Taylor, KG Barber, CA Lee… - International Journal of …, 2023 - mdpi.com
There are~ 463 million diabetics worldwide, and more than half have diabetic retinopathy.
Yet, treatments are still lacking for non-proliferative diabetic retinopathy. We and others …

[HTML][HTML] RORγt inhibitor-SR1001 halts retinal inflammation, capillary degeneration, and the progression of diabetic retinopathy

TE Zapadka, SI Lindstrom, BE Taylor, CA Lee… - International Journal of …, 2020 - mdpi.com
Diabetic retinopathy is a diabetes-mediated retinal microvascular disease that is the leading
cause of blindness in the working-age population worldwide. Interleukin (IL)-17A is an …

[HTML][HTML] Efficacy and safety of Faricimab for macular edema due to retinal vein occlusion: 24-week results from the BALATON and COMINO trials

R Tadayoni, LP Paris, CJ Danzig, F Abreu, AM Khanani… - Ophthalmology, 2024 - Elsevier
Purpose To evaluate the 24-week efficacy and safety of the dual angiopoietin-2 (Ang-2) and
vascular endothelial growth factor (VEGF)-A inhibitor faricimab versus aflibercept in patients …